Tau protein (β transferrin or asialo-transferrin) is present in cerebrospinal fluid (CSF) and is used as a marker for the identification of CSF leakage from the nose, the ear, the eyes or from the head/neck wound after an injury.
An example of positive Tau protein.
This blot shows positive identification of CSF in nasal fluid. In tracks 3, 4, and 5 there are two bands, in the same position as the control CSF (track 1).
An example of negative Tau protein.
This nasal fluid does not contain CSF as it resembles the pattern seen with serum control (track 2).
Key: 1 = control CSF, 2 = control serum, 3 = neat nasal fluid, 4 = 1/5 diluted nasal fluid and 5 = 1/10 diluted nasal fluid