Tau protein (β transferrin or asialo-transferrin)

Tau protein (β transferrin or asialo-transferrin) is present in cerebrospinal fluid (CSF) and is used as a marker for the identification of CSF leakage from the nose, the ear, the eyes or from the head/neck wound after an injury.

An example of positive Tau protein.
+ (anode)

 

 

 

 

 

This blot shows positive identification of CSF in nasal fluid. In tracks 3, 4, and 5 there are two bands, in the same position as the control CSF (track 1).

An example of negative Tau protein.
+(anode)

  

 

 

 

 

This nasal fluid does not contain CSF as it resembles the pattern seen with serum control (track 2).

Key: 1 = control CSF, 2 = control serum, 3 = neat nasal fluid, 4 = 1/5 diluted nasal fluid and 5 = 1/10 diluted nasal fluid