Programme

The meeting will include investigators at all levels – from group leaders to post-doctoral staff and students, with the emphasis on younger people.

The aim is to promote ideas and interactions, avoiding a simple series of individual lectures. We will do our level best to have as many as possible delegates giving talks, with plenty of time for discussion. There will also be room for posters.

day one

 Programme

 
  Thursday 6th November
 12.00 Arrival and lunch 
 13.25 Welcome
Paul Moss 
  Lytic infection and genomics
  Chair: Blair Strang
 13.30 Richard Stanton
Focus on HCMV strains and tropism
 14.00 Blair Strang
The architecture of HCMV replication compartments
 14.15 Matthew Reeves 
Heterochromatin protein 1 and the regulation of viral gene expression: beyond chromatin?
 14.30 Gavin Wilkie
High-throughput sequencing of complete HCMV genomes directly from clinical material reveals the common occurrence of mutants
 14.45 Finn Grey
Focus on miRNAs
 15.15 Amie Regan
Functional analysis of CMV miRNAs
 15.30 Kevin Robertson
MicroRNA-342-5p couples antiviral immunity to the sterol metabolic network
 15.45 Refreshments 
 Latent infection
 Chair: Matthew Reeves
 16.15 Emma Poole
Focus on latency
 16.45 Jonathan Lau
HCMV latency-associated protein LUNA is associated with transcriptional regulation of viral gene expression via ade-SUMOylase activity
 17.00 Benjamin Krishna
Latency-associated expression of the US28 gene allows targeting of latently infected cells with a novel immunotoxin
 17.15 Close
 19.00 Drinks Reception and Dinner at Horton Grange
Drinks reception from 19.00
Dinner served from 19.30

 

day two
   
 Friday 7th November 
 Immunity
 Chair: Mark Wills
 09.00 Speaker to be confirmed 
Focus on immunology
 09.30 Helen Parry
The CD4 immune response to CMV inchronic lymphocytic leukaemia
 09.45 Louise Hosie
HCMV-mediated memory-inflation towards a HLA-C-restricted epitope
 10.00 Mathew Clement
IL-10 receptor-mediated suppressionof anti-CMV T-cell immunity: in mice and men
 10.15 Sarah Jackson
Direct control of viral dissemination by HCMV-specific CD8+ T cells
 10.30 Annette Pachnio 
Differences in cellular localisation of CMV glycoproteins greatly influences their potential as T cell targets
 10.45 Maria Stacey 
Insight into the influence of hostgenetics on CMV infection in vivo
 11.00 Refreshments
  Immune modulation
  Chair: Ian Humphreys
 11.30 Peter Tomasec
Focus on immune modulation
 12.00 Dick van den Boomen
A characterisation of the host machinery and substrate-specificity of HCMV US2 and US11
 12.15 Ceri Fielding
HCMV US18 and US20 regulate natural killer cell activating ligands
 12.30 Kevin Chen
Differential recognition of HCMV by natural killer cell subsets through LIR1-UL18 interaction
 12.45 Lunch 
  Clinical virology
  Chair: Lars Dölken
 14.00 Matthew Bates
Prevalence and risk factors for betaherpesvirus DNAemia in infants aged between 3 weeks and 2 years of age, admitted to a large referral hospital in sub-Saharan Africa
 14.15 Dimitrios Chanouzas
CD4+CD28- T-cell expansions in ANCA-Associated Vasculitis are associated with arterial stiffness: Preliminary results from a clinical trial investigating the potential of valaciclovir to reduce CD4+CD28- T-cell expansion.
 14.30 David Webster
Immunopathogenesis of granulomatous-lymphocytic interstitial lung disease (GLILD) in common variable immunodeficiency (CVID) – a role for CMV
 14.45 Paul Griffiths
Focus on clinical virology and vaccines
 15.15 Farewell 
 15.20 Refreshments and departure 

 

posters
   
 Posters 
 1 Marco Michalski  
Analyzing changes in nuclear architecture and transcriptional activity during lytic MCMV infection by Hi-C and 4sU-tagging
 2 Hongjin Lu
SREBP2-independent mechanism for25-hydroxycholesterol inhibition of viral growth mediated by the sterol biosynthesis pathway
 3 Pairoa Praihirunkit
Identification of cellular genetargets of anti-viral miR-27
 4 Julia Colston
Dissecting CD8+ T cell memory inflation using a simplified murine model
 5 Jawaher Abdulhakim
Investigating the efficiency of CMV DNA detection from DBS
6 Zahrah Buhamad
Identification of CMV glycoprotein genotypes using molecular techniques
Posters can be displayed throughout the duration of the conference.  Posters should be no larger than A0 portrait, 841 x 1189 mm

The Medical School Events Office offers a bespoke Poster Printing service for conferences and events, we will even hang your poster in the allocated space ready for the start of the event.  Just make sure you let us know its for the UK CMV Conference.