We offer users a 45 sqm wet-lab stocked with the consumables and equipment needed for NMR sample preparation; access to other biophysical tools can also be arranged.
Equipment available in the NMR laboratory
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centrifuges for NMR sample tubes and eppendorf tubes
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chemical fumehood
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dryer for tubes
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freezers (-20º and -80ºC)
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pH meter for NMR sample tubes
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refrigerators t
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ube cleaner
Consumables including 5 mm NMR tubes, deuterated buffers, DMSO and D2O are available at cost from Sue Rhodes.
The Birmingham Structural Biology Forum offers additional facilities for biophysical analysis of proteins including:
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Atomic Force Microscopy
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Calorimetry
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Circular Dichroism
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Fluorescence
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FT-ICR mass spectrometry
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Infrared Spectroscopy
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Surface Plasmon Resonance
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X-ray crystallography
We are members of the Technology Hub which provides a range of facilities.
The Protein Expression facility in the School of Cancer Sciences offers:
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Fermentation (E coli, Pichia) in three refrigerated incubator shakers and two fermentors
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Protein purification systems: two AKTA Prime and two AKTA Purifier chromatography systems
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Cell lysis by French Press, Emulsiflex and sonicator
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UV-VIS spectrophotometer
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Thermofluor 96 well plate screening for NMR conditions and ligands
The floorplan of the NMR building shows the position of the laboratory
