Molecular mechanisms in immune cell differentiation and function Molecular mechanisms in immune cell differentiation and function (20 credits) This module will provide an in depth knowledge of the development of primary and secondary lymphoid structures, and how T and B cells differentiate within these environments. Cutting-edge knowledge will also be developed in the activation and functional diversity of T and B cell responses, including the formation of germinal centres, T helper cell differentiation and regulatory T cell function. The cellular requirements, molecules and their associated signalling pathways, required for each of these processes will be covered. The module will contain a combination of face-to-face lectures integrated with a series of small group teaching sessions to provide further tuition and clarification of understanding. Module attendance required: Three weeks of lectures and small group tutorials. Module dates: TBC Assessment: Examination (75%): 2 written essays. (2h exam) Coursework (25%): Course work will consist of a written 1500 word summary document and oral presentation of a given research topic, bringing together information from a number of cutting-edge research publications. Length of presentation limited to 25 minutes with 5 minutes for questions. Academics involved in the delivery of this module: Dr Jorge Caamano (Institute for Biomedical Research) and Dr John Curnow (Centre for Translational Inflammation Research), and a number of other researchers from across the College of Medical and Dental Sciences, including Prof. Peter Cockerill, Prof. Adam Cunningham, Dr Will Jenkinson, Dr Kai Toellner, and Dr David Withers.