Research activity

Here is a list of all the research activity pages:

Generic List

REFER (REFer for EchocaRdiogram) - A Prospective Validation of a Clinical Decision Rule, NT-proBNP, or their combination, in the Diagnosis of Heart Failure in Primary Care

Description
Index page for the REFER (REFer for EchocaRdiogram) Trial - A Prospective Validation of a Clinical Decision Rule, NT-proBNP, or their combination, in the Diagnosis of Heart Failure in Primary Care - at the University of Birmingham.

Regulation of Haematopoietic Cell Differentiation

Description
The mammalian blood cell system provides cell biologists with one of the best experimental models in which to unravel how one stem cell – the haematopoietic stem cell – gives rise to the many different types of cells of the blood and immune systems. The classic model for this process depicts two families of cells; lymphoid and myeloid. This dichotomy has been increasingly challenged in recent years – to the extent that the accumulation of new findings culminated in a Nature commentary suggesting that "the latest research will necessitate revision of textbook accounts". We proposed the 'Pair-wise Relationships Model' of haematopoiesis, which is an updated version of our 'Sequential Determination Model' (proposed in 1985). Our model groups the pair-wise relationships between lineage fates around a broken circle: to date there aren't findings that refute this model. Ongoing studies are examining whether our model is a correct representation of haematopoiesis by extending understanding of the events that govern commitment of haematopoietic stem cells to becoming one particular type of cell. Endeavours to understand the controls that drive cell differentiation are focussed on signals that arise from all-trans retinoic acid and vitamin D3. We are also interested in the use of novel retinoids to modulate haematopoiesis and the behaviour of malignant cells.

Reproduction, Embryology & Paediatrics

Description
This theme primarily addresses the health and disease processes that effect Women's Health, mother's wellbeing during pregnancy and children, with research spanning the breadth of laboratory based science (such as molecular biology) to translational research in the form of critical appraisal of the literature and interventional trials.

Reproduction, genetics and development research

Description
Reproduction, genetics and development research at University of Birmingham covers areas from the laboratory bench to the clinical work place in areas of clinical and molecular genetics, reproduction, women's and children's health. There are close collaborations between the areas of research theme. We have state-of-the-art laboratories in the IBR that are working on aspects of molecular genetics, including animal model through to close liaisons with the Centre for Endocrinology, Diabetes and Metabolism in Reproduction and Children's' Health. The research performed is directed into 'translational and clinical areas' of genomic medicine, rare diseases, reproductive medicine and endocrinology, fetal health and disease

Research - School of Mechanical Engineering

Description
Homepage for research at the School of Mechanical Engineering

Research and Training Centre in Physical Sciences for Health

Description
This page is the home site of the Research and Training Centre in Physical Sciences for Health (PSIBS DTC) at the University of Birmingham, established by EPSRC for the high-quality research and pioneering development of biomedical imaging techniques. These techniques are inherently interdisciplinary, drawing upon chemistry, physics, computer science and other subjects to build an integrated approach to postgraduate study across a wide spectrum of physical sciences at the life sciences interface.
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