The University of Birmingham hosts theMRC Midland Hub for Trials Methodology Research, one of the seven research facilities in the MRC Network of Hubs. This facility is dedicated to providing research, training and advice on methodology to trial practitioners. Key areas of research expertise and research activity include (i) quality of life evaluation for clinical and health economic assessment (ii) discovery and evaluation of diagnostic, prognostic and predictive biomarkers (iii) phase II clinical trials (iv) evaluation of non-drug interventions, particularly radiotherapy (v) trials in rare diseases (vi) time-to-event analysis (vii) issues in trial conduct (viii) Bayesian methods (ix) systematic reviews and decision modelling for clinical and health economic evaluation. http://www.birmingham.ac.uk/research/activity/mds/centres/bcct/infrastructure/index.aspx?RelatedItemsList_SyndicationType=1 Contensis: http://www.contentmanagement.co.uk