Research in Cardiovascular Sciences in the College of Medical and Dental Sciences and the College of Life and Environmental Sciences in the University of Birmingham is co-ordinated through the Centre for Cardiovascular Sciences by a steering group that is chaired jointly by Professor Steve Watson and Professor Gregory Lip. Current members of the steering group include Professor Roy Bicknell, Professor Gerard Nash, Professor Paulus Kirchhof, Professor Prem Kumar, Dr John Townend, Professor Janice Marshall, Professor Kate Jolly, Professor David Fitzmaurice, and Professor Thomas Dietrich.
The Centre plays a key role in developing the strategy in cardiovascular sciences and in the appointment of new group leaders. The Centre runs an active seminar programme and co-ordinates annual away days. The research in the Centre for Cardiovascular Sciences ranges from basic aspects of cardiovascular biology, through to animal models, the clinic and the community.
Research is divided into four main groupings:
In CCS, key areas of study are the pathophysiology of heart failure, novel techniques for cardio-protection during surgery and following ischemic reperfusion injury, the role of thrombosis and haemostasis in atrial fibrillation, and new approaches to management of life-threatening cardiac arrhythmias.
In CRIC, research focuses on the physiological and pathological processes underlying systemic cardiovascular and respiratory homeostasis in health and disease. The group is particularly distinguished by its use of in vivo techniques and its emphasis on systemic integration. A key topic is the impact of acute and chronic disturbances of oxygen delivery and utilisation in human and animal models.
Primary Care and Population Cardiovascular Sciences (PCPCS)
PCPCS covers a mature and expanding programme encompassing several large longstanding research groups investigating cardiovascular risk factors, health service implementation and behaviour modification for prevention at a population and primary care level. The areas of research include primary prevention, cardiovascular risk screening and treatment of heart failure, atrial fibrillation, anticoagulation and stroke. The close collaborations between these groups enables them to maximise their expertise in cardiovascular epidemiology, clinical trials, translational diagnostics and, unusually, rapid translation of research into clinical practice.
In VITA, key areas of research are platelet biochemistry and clinical platelet bleeding disorders, physiological and cancer-regulated angiogenesis, with a special interest in endothelial-specific genes, and the roles of leukocyte-endothelial cell interactions in vascular pathology.