Current research focuses on 4 key areas:
Immune regulation in liver disease
-
The role of specific adhesion molecules and chemokines in the regulation of lymphocyte recruitment to the liver and gut
-
The role of dendritic cells in regulating local immune responses in the liver
-
Function of TNF receptor family members in controlling cellular activation and death.
Hepatitis virology and immune evasion
-
Determinants of cell tropism for hepatitis viruses
-
Immune evasion by hepatitis C and hepatitis B
Primary liver cancer
-
Gene therapy and novel therapeutic interventions in hepatitis and non-hepatitis associated primary liver cancer
-
Immune responses to hepatocellular carcinoma and cholangiocarcinoma and biomarkers for these cancers
Tissue Injury and Transplantation
-
Immunity and cell-mediated injury in the liver
-
Molecular regulation of ischemia reperfusion and pre-conditioning in the liver
-
Regulation of inflammation in the liver