Neurodegeneration encompasses a large group of diseases associated with specific pathology and neuronal death in different parts of the nervous system.
Our team works on a wide range of topics relating to acute and chronic neurodegenerative diseases. Current research programmes concern the genetics and cellular pathology of neurodegenerative diseases such as Alzheimer’s disease, Parkinson’s disease, Motor Neurone Disease, Multiple Sclerosis and Glaucoma.
Based on our understanding of the cellular pathology associated with these diseases we aim to develop early disease biomarkers and novel therapeutic interventions, including gene therapy. The variety of basic research programmes is complemented by clinical programmes, including therapeutic trials in dementia, Motor Neurone Disease and Parkinson’s disease.
The clinicians of the team have established valuable DNA and serum banks (PD, MND, PSP, MSA) and initiated sample collection from dementia patients for the local tissue repository.