Research Fellow - Post number 49425
We seek to appoint a motivated individual for 18 months to a Wellcome Trust Programme grant to to characterize the phenotype of two newly developed mouse models defective for a key molecular mechanism for platelets/stromal cell interaction. The two mouse models are inducible CLEC-2 and Podoplanin-deficient mice. The appointee will use a series of cell biology and in vivo techniques to study the interaction between platelets and stromal cells including their response in various inflammatory models. This is highly interdisciplinary project that bridges the field of development and immunity and will require a candidate with a strong immunological background that has a large experience in animal work. Experience in flow cytometry, confocal microscopy, molecular biology and animal licence (module 1-4) is required while experience with transgenic mice and ability to use FACS sorter is preferred. The candidate should have a PhD or post-doctoral experience that addresses these or similar issues. He/she must have excellent academic qualifications, strong initiative and good teamwork skills. Previous experience of working as part of a collaborative team is desirable.
Further information and an application can be submitted via the University vacancy website.
Closing date: March 28 2012