Biomaterials - keratinocyte cell sheet grown in vitroThe Biomaterials research theme, centred at the School of Dentistry, explores a diverse range of research topics, ranging from dental biomaterials through to microbiological responses to biomaterials and the tissue engineering of bone and oral mucosa.

The research is both basic and translational, and is focussed on the properties and performance of biomaterials and their interactions with host tissues at both the cellular and clinical levels.

Innovative research is underway to develop novel ceramic, resin-based and cement-based biomaterials for dental and orthopaedic applications and to study the properties and biocompatibility of these new biomaterials. A pivotal goal of our research is to optimise cell and tissue interactions with new biomaterials and, where possible, correlate this with clinical performance.

While some aspects of our research activities bring new focus on more traditional dental materials, others approach novel tissue engineering and biomimetic solutions that may allow functional adaptation of implanted materials for bone replacement and non-line of sight coating of materials with nanoparticulate hydroxyapatite. Our interdisciplinary research, combining cellular and molecular biology, materials science, imaging and clinical dentistry, has broad applicability, which, although having a base within dentistry, is applicable to many other disciplines.