Immunity, Inflammation and Infection


Immunity and infection research at University of BirminghamThe World Health Organisation has estimated that every hour 1500 people will die of an infectious disease. In the UK almost 2 million people suffer from chronic immune-regulated inflammatory diseases such as Rheumatoid Arthritis.  Chronic liver disease is the only major cause of death increasing year on year in the UK.  Research by basic scientists and clinical researchers at Birmingham investigates fundamental mechanisms involved in bacterial and viral infection,  immune regulation, immune mediated inflammation  and explores changes in health, disease and old age.

We employ a large and successful cohort of internationally recognised scientists. Key disease areas include Rheumatoid Arthritis, inflammatory liver and kidney disease, lupus, ocular inflammation, cancer, hepatitis C, bacterial pathogenesis and antibiotic resistance. Our basic and translational strengths have been  recognised through award of external funding to support a number of centres of excellence including the MRC Centre for Immune Regulation; the MRC/ARUK Centre for Musculoskeletal Ageing; the National Institute for Health Biomedical Liver Research Unit (NIHR- BRU) in Liver and the ARUK Centre for Pathogenesis.  We are developing new university funded centres of excellence such as the Institute for Microbiology and Infection, the Centre for Human Virology and the Centre for Translational Inflammation Research.  These investments  allow us to build clear platforms for translation of our basic laboratory work into cell and immunotherapy trials and development of new diagnostic tests and potential vaccines.

Value is added to our research groups through the provision of state of the art laboratory facilities and an excellent range of key technologies. Translation to and from patients is facilitated through good links with clinical colleagues and infrastructure arrangements with local Trusts and other partnership organisations such as the Health Protection Agency.

Research Themes