Key cancer research groups and the CRUK Clinical Trials Unit (CRCTU) are located in contiguous buildings at the west end of the Medical School campus. Since 2008 substantial investment has provided high quality accommodation for the CRCTU allowing the unit to extend its portfolio of academic trials and thereby to increase income to sustain future developments.
The CRCTU is the largest cancer trials unit in the UK (134 staff) with expertise in late phase trials, development of novel therapeutics and biomarkers in clinical trials. In 2009 the CRCTU was awarded core funding to become the UK’s designated clinical trials unit for paediatric malignancies. CRCTU has recruited 4478 patients into 56 trials since 2008. The CRCTU also hosts the NIHR BRU in Liver Disease extending expertise in early phase trials in cancer into non-malignant diseases an example of how we disseminate skills to maximise delivery.
The NIHR Experimental Cancer Medicine Centre (ECMC) focuses on early phase translational activity and includes a paediatric ECMC at Birmingham Children’s Hospital leading childhood phase 1/2a trials. The Centre for Clinical Haematology, built with Regional Development Agency funds in 2011, houses the national Leukaemia and Lymphoma Research Therapy Acceleration Programme. Coordination of national trials activity through the TAP has greatly increased recruitment and income allowing us to expand the Centre into adjacent space to increase capacity.