About

 ROSSINI is a prospective, multicentre, observer-blinded randomised controlled trial which aims to establish whether the use of a wound-edge protection device in adult patients undergoing laparotomy leads to a lower rate of surgical site infection (SSI).

Secondary outcomes to be explored include establishing the efficacy of the device against various degrees of wound contamination and related patient comorbidity, as well as assessing the safety and cost-effectiveness of the device and its effect on health-related quality of life.

ROSSINI is the first prospective multicentre trial from the West Midlands Research Collaborative. This collaborative consists of Surgical Registrars and Specialist Trainees from the region who, with the support of the Birmingham Clinical Trials Units, the Birmingham Research Design Service and the Academic Department of Surgery, have designed the study and will be primarily responsible for the ongoing conduct of the trial.