Systematic reviews and meta-analyses of diagnostic test accuracy 2017

Who is this course for?

This three-day course is organised jointly by faculty from the University of Birmingham and the University of Amsterdam. The course is designed for individuals undertaking health technology assessment, health service researchers and healthcare professionals interested in understanding key issues in the design and conduct of systematic reviews and meta-analyses of diagnostic test accuracy (DTA) studies. The course will be delivered through a mixture of interactive presentations, discussions and hands-on computer exercises.

Date: Monday 4 September to Wednesday 6 September 2017 

 

Course requirements: Participants should bring a laptop with STATA and RevMan 5 installed. RevMan is free to download. Stata is a commercial statistical package so if you do not have the package, we will provide a license that will give you complementary use for a limited period. Instructions for downloading software and course materials will be provided prior to the start of the course.

Venue: etc.venues (Maple House), 150 Corporation Street, Birmingham B4 6TB

Learning objectives

At the end of the course, participants should be able to:

  • Appreciate the diversity of test usage and study designs
  • Understand potential risk of bias and concerns regarding applicability
  • Understand the concept underlying approaches to meta-analysis
  • Explore heterogeneity
  • Create different types of analysis (in RevMan and Stata)
  • Summarise results and draw appropriate conclusions

Course faculty

  • Patrick Bossuyt, Professor (Clinical Epidemiology)
    Department of Clinical Epidemiology and Biostatistics, Academic Medical Center
    University of Amsterdam, The Netherlands
  • Jon Deeks, Professor (Biostatistics)
    Institute of Applied Health Research, University of Birmingham, UK
  • Clare Davenport, Senior Clinical Lecturer
    Institute of Applied Health Research, University of Birmingham, UK
  • Mariska Leeflang, Epidemiologist
    Department of Clinical Epidemiology and Biostatistics, Academic Medical Center
    University of Amsterdam, The Netherlands
  • Sue Mallett, Senior Lecturer in Medical Statistics
    Institute of Applied Health Research, University of Birmingham, UK
  • Yemisi Takwoingi, Senior Research Fellow in Biostatistics
    Institute of Applied Health Research, University of Birmingham, UK

Course fee: £695 (includes course materials, a light breakfast, 2-course lunch and unlimited tea or coffee on the 3 days). Cochrane is sponsoring free registration for three Cochrane DTA review authors. To be eligible, you must have at least a registered title for a Cochrane DTA review and apply by the 2nd of June. In the first instance, only one author of an author team will be eligible and priority will be given to applicants from outside Europe. If you think you qualify for sponsored registration, please contact Natasha Maguire (email: N.L.maguire@bham.ac.uk) for a course application form. The form should be returned along with a supporting letter from your Cochrane Review Group Co-ordinating Editor or Managing Editor indicating the stage of your review and your commitment to completing the review. Successful applicants will be notified by 9th of June.

Registration: To book a place and make payment, please go to the online shop.  Registration closes 30th June 2017 or earlier if the course is fully booked.

For enquiries, please contact: Natasha Maguire (email: N.L.Maguire@bham.ac.uk)

Programme


 

Monday 4th   

 

 

Tuesday 5th  

 

 

Wednesday 6th

 

 

 

8:30 – 9:00

COFFEE

8:30 – 9:00

COFFEE

 

9:00 – 9.30

REGISTRATION & COFFEE

9:00 – 9.45

8: Basic meta-analysis of test accuracy

 

8:30 – 10:00

15a: Practical – Using Stata for test comparisons and investigations of heterogeneity

9:00 – 10:00

15b: Atypical test accuracy questions

 

 

9:30 – 10:00

Introduction and overview of course

9:45 – 10:30

9: Hierarchical meta-analytic models

 

10:00 – 10:30

16: Understanding and re-expressing results

 

10:00 – 10:30

1: Systematic review process

10:30 – 11:00

COFFEE

10:30– 10:50

COFFEE

 

10:30 – 11:15

2: Introduction to test accuracy

11:00 – 12:30

10: Practical – Using RevMan and Stata for meta-analysis of a single test

 

10:50 – 11:40

17: Exercise – Interpretation and drawing conclusions

 

11:20 – 12:00

3: Study designs & reference standards

11:45 – 12:30

18: Presenting results and summary of findings tables

 

12:00 – 1:00

LUNCH

12:30 – 1:30

LUNCH

12:30 – 1:30

LUNCH

 

1:00 – 1:40

4: Sources of bias and variability

1:30 – 2:20

11: Test comparisons & meta-regression

 

1:30 – 2:30

19: Recommendations for practice – accuracy in the evaluation of tests

 

1:45 – 2:30

5: Formulating a DTA review question and eligibility criteria

 

2:35 – 3:20

6: Methodological quality assessment and QUADAS-2

 

2.25 – 3:10

12: Investigating heterogeneity & sensitivity analysis

 

 

2:30 – 3:00

Discussion, questions and feedback

 

3:20 – 3:40

COFFEE

3:10 – 3:30

COFFEE

 CLOSE

 

 

3:40 – 4:40

7: Exercise – Data extraction and quality assessment

3:30 – 4:15

13: Planning analyses

 

 

 

 

4:20 – 5:15

14: Practical – Using RevMan for test comparisons and investigations of heterogeneity

 

4:40 – 5:00

Discussion

5:15 – 5:30

Discussion

 

 

Accommodation

Maple House is located in Birmingham City Centre with several hotels close by, including Staybridge Suites (One Martineau Place, 44-80 Corporation St, Birmingham B2 4UW) and Holiday Inn Express (Snow Hill Plaza, Birmingham B4 6HY).

Venue and directions

Maple House is located in the great Birmingham City Centre location of Corporation Street overlooking Old Square. Just minutes from New Street, Snow Hill and Moor Street train stations, the venue is also conveniently located for a number of major bus routes. Parking is available at a number of NCP car parks locally. Maple House has reduced parking rates agreed at High Street/Albert Street NCP (Dale End, B4 7LN) and Londonderry House NCP (Dalton Street, B4 7LX).

Find out more

Under the auspices of:

EFLM