Transanal Endoscopic Microsurgery (TEM) and Radiotherapy in Early Rectal Cancer (TREC)

TREC Trial Objectives: 

The aim of the TREC pilot study is to assess the feasibility and inform the design of a large, multi-centre randomised study comparing radical surgery versus radiotherapy plus local excision for early rectal cancer. Data will be obtained to allow accurate sample size estimation and to refine the primary outcome measures for the Phase III TREC trial.

ISRCTN Number:  14422743

Funder: Cancer Research UK

Sponsor: University of Birmingham

Chief Investigator: Mr Simon Bach