PD SURG is a large, pragmatic, multicentre “real-life” randomised trial to evaluate the role of surgery as therapy for PD. The fundamental question being addressed in this trial is:
Does early surgery provide more or less effective long-term control than medical therapy (with surgery deferred for as long as possible)?
In order to obtain the large number of patients needed to provide reliable answers, and to maximise the clinical relevance of the findings, the trial was designed to fit in with routine practice as far as possible and to impose minimal additional workload by keeping extra clinic-based tests and evaluations to a minimum (the majority of assessments are by postal questionnaires to patients and carers). Publication of the results will be in the name of the collaborative group and not those of the central organisers.