Staff within this research theme 

Collectively, members of the Molecular Cell Biology and Signalling (MCBS) theme possess expertise in a broad spectrum of techniques.

Dr Lindsey Jane Leach

Dr Lindsey Jane Leach

Birmingham Fellow

Dr Leach joined the University of Birmingham as a Birmingham Fellow in 2012 and is based in the Plant Genetics and Cell Biology group in the School of Biosciences. Her work involves using statistical genetics and bioinformatic approaches to dissecting the genetic architecture of quantitative trait variation.

Telephone +44 (0)121 414 5883

Email l.j.leach@bham.ac.uk

Professor John Heath

Professor John Heath

Director of the Centre for Systems Biology

Telephone +44 (0)121 41 47533

Email j.k.heath@bham.ac.uk

Professor Chris Bunce

Professor Chris Bunce

Professor of Experimental Haematological Oncology

Professor Chris Bunce Directs a translational research group dedicated to the development of novel therapies for leukaemias and lymphomas. A particular focus is the exploitation of drug redeployment strategies using off- patent drugs to provide affordable therapies that can be exploited by all including the worlds poorer nations.

Telephone +44 (0)121 41 43770

Email c.m.bunce@bham.ac.uk

Dr Juliet Coates

Dr Juliet Coates

Lecturer in Plant Molecular Genetics

My research interest is in understanding development and evolution, particularly in plants. I run a small research group who work primarily with moss and Arabidopsis; we also grow liverworts, spikemoss, grasses and green seaweeds. We use molecular genetics, cell biology and ‘omics approaches to understand gene and protein function in these systems.

Telephone +44 (0)121 41 45478

Email j.c.coates@bham.ac.uk

Dr Saverio Brogna

Dr Saverio Brogna

Principal Investigator

Dr Brogna is interested in eukaryotic gene expression and RNA processing. He has published some significant papers on these subjects. At present he is researching the Nonsense Mediated mRNA Decay (NMD) phenomenon and the mechanisms that connect pre-mRNA processing with translation.

Telephone +44 (0)121 41 45569

Email s.brogna@bham.ac.uk

Dr Carina Hellberg

Dr Carina Hellberg

Reader in Molecular Cell Biology

Dr Carina Hellberg is an expert on protein tyrosine phosphatase signalling. She is currently investigating how phosphatases regulate platelet-derived growth factor receptor signal transduction. In addition, she is investigating how oncogenes affect receptor signalling by altering the intracellular receptor sorting.

Telephone +44 (0)121 41 42652

Email c.hellberg@bham.ac.uk

Dr Alicia Hidalgo

Dr Alicia Hidalgo

Reader in Developmental Neurobiology

Our lab aims to understand how the nervous system – including the brain – is formed and works.

Telephone +44 (0)121 41 45416

Email a.hidalgo@bham.ac.uk

Dr Neil Hotchin

Dr Neil Hotchin

Senior Lecturer in Molecular Cell Biology
Director of the Biosciences Graduate Research School

Dr Hotchin is a cell biologist with an interest in normal epithelial cell function and in understanding the processes that contribute to diseases such as cancer. He has published a number of high impact papers on the role of small GTP-binding proteins in control of epithelial cell function. In addition to his research and teaching activities, Dr Hotchin is also currently Director of the ...

Telephone +44 (0)121 41 45412

Email n.a.hotchin@bham.ac.uk

Dr Aditi Kanhere

Dr Aditi Kanhere

Dr Aditi Kanhere’s research focuses on understanding how non-coding RNA, transcription factors and epigenetic modifications regulate gene expression changes in normal and diseased conditions. Her laboratory integrates cutting-edge genomics technologies with computational methods to understand mechanisms of transcription regulation in cancer.

Telephone +44 (0)121 41 45896

Email a.kanhere@bham.ac.uk

Professor R.H. (Bob) Michell

Professor R.H. (Bob) Michell

Emeritus Professor of Biochemistry
formerly Royal Society Research Professor at the University of Birmingham

Since the 1960s Bob Michell has been one of the pioneers in revealing the diverse biological functions of inositol lipids in eukaryote cells.  He had major roles in establishing that receptor-controlled phospholipase C hydrolysis of PtdIns(4,5)P2 is a signaling reaction and that PtdIns(3,5)P2 is a regulator of intracellular trafficking processes. 

Telephone +44 (0)741 1792640 /+44 (0)121 4721356

Email r.h.michell@bham.ac.uk

Dr Francesco Michelangeli

Dr Francesco Michelangeli

Telephone +44 (0)121 41 45398

Email f.michelangeli@bham.ac.uk

Dr Steve Publicover

Dr Steve Publicover

Reader

Dr Steve Publicover is an internationally-recognised expert on sperm physiology and signalling events in sperm initiated by sperm-egg interaction.

Telephone +44 (0)121 41 45455

Email s.j.publicover@bham.ac.uk

Dr Joshua Rappoport

Dr Joshua Rappoport

60 second video iconFor over fifteen years Dr Rappoport's research has focused upon the mechanisms by which biologically relevant molecules traffic into and out of cells.  In particular Dr Rappoport's lab develops and applies innovative microscopy techniques to visualise the internalisation into cells of cargo relevant to human health.  Along with collaborators at The University of ...

Telephone +44 (0)121 41 49019

Email j.rappoport@bham.ac.uk

Dr Janet Smith

Dr Janet Smith

Telephone +44 (0)121 41 45408

Email j.smith.20@bham.ac.uk

Dr Matthias Soller

Dr Matthias Soller

My prime research interest is how the information encoded in chromosomes instructs building of the most complex organ, the brain, and allows an organism to perform elaborate tasks.

Telephone +44 (0)121 41 45905

Email m.soller@bham.ac.uk

Dr Michael Tomlinson

Dr Michael Tomlinson

Senior Research Fellow

Dr Mike Tomlinson has an international reputation in the two fields of platelets and cell surface biology, and has published in numerous edited books and scientific journals in these areas. He has been invited to speak at major international conferences, including Gordon Research and FASEB Summer Conferences in the United States, and organised the 4thEuropean Conference on Tetraspanins in ...

Telephone +44 (0)121 41 42507

Email m.g.tomlinson@bham.ac.uk

Professor Mark Wheatley

Professor Mark Wheatley

Chair of Biochemical Pharmacology

Professor Mark Wheatley has an international reputation for his research into the structure and function of G-protein-coupled receptors (GPCRs). He has national and international collaborations with both academia and the pharmaceutical industry.

Telephone +44 (0)121 41 43981

Email m.wheatley@bham.ac.uk

Dr Yun Fan

Dr Yun Fan

Birmingham Fellow

Dr Yun Fan’s research interest centers on understanding how cell death, cell proliferation, and cell differentiation are coordinated to maintain tissue homeostasis.  This has important implications for cancer development and tissue regeneration.  As one of our Birmingham Fellows recruited worldwide, he joined us and established his laboratory at Birmingham in 2012.

Telephone +44 (0)121 41 48513

Email y.fan@bham.ac.uk