Exploiting somatic hypermutation to create new drugs and probe protein structure
Professor Nick Brindle
Department of Cardiovascular Sciences, University of Leicester
Nick Brindle is based at the University of Leicester where he holds a Chair in Cell Signalling in the Department of Biochemistry and the Department of Cardiovascular Sciences. He has a long standing interest in receptor tyrosine kinases and over the past ten years has worked mainly on angiopoietin signalling. Work in this area include discovery of a new signalling pathway, novel protein:protein interactions and defining a key mechanism by which angiopoietin signalling is regulated at the level of the receptor. Currently his group is focused on understanding structure and function of signalling proteins and developing protein therapeutics using protein engineering, structural and evolutionary approaches.
Please contact Roy Bicknell (firstname.lastname@example.org) directly if you would like to meet with Professor Brindle.