Monocarboxylate (lactate) transporters (MCTs): structure, roles, regulation and potential as therapeutic targets
Professor Andrew Halestrap
School of Biochemistry and the Bristol Heart Institute, University of Bristol
Andrew Halestrap is Professor of Biochemistry at the University of Bristol and a member of The Bristol Heart Institute. His research interests include monocarboxylate (lactate) transport across cell membranes and the role of mitochondria in the healthy and diseased heart, especially in relation to reperfusion injury and cardioprotection. The focus of his current work on monocarboxylate transporters is on the relationship between their structure and function, with particular emphasis on the development of isoform-specific inhibitors that may be used in cancer chemotherapy. He is a Fellow of the Academy of Medical Sciences and the current Chair of the British Heart Foundation Project Grants Committee. He was awarded Keilin Memorial Lecture of the Biochemical society in 2010.