Into thin air: Regulation of gene expression by hypoxia
Professor Cormac Taylor, UCD Conway Institute of Biomolecular and Biomedical Research, School of Medicine & Medical Science, Conway Institute, Dublin
Cormac Taylor currently holds an appointment as Associate Professor of Cellular Physiology at the School of Medicine and Medical Science and the Conway Institute, University College Dublin. He has published over sixty original research papers and given over eighty invited national and international presentations. Current research in Cormac’s group is directed towards expanding our understanding of the physiological and pathophysiological mechanisms by which changes in microenviornmental oxygen and carbon dioxide levels regulate gene transcription in eukaryotic cells. A key focus of this work is the identification of new therapeutic targets in inflammatory disease. Key discoveries from the Taylor lab include the identification of a major mechanism linking hypoxia to inflammation and the discovery that carbon dioxide may be an important signaling molecule in the regulation of gene transcription in mammalian cells.