Research in the School

ResearchThe School of Clinical and Experimental Medicine focuses on a number of research areas, and provides a coherent management and support structure for these which facilitates cross-disciplinary interactions and clinical access and hence translation of basic research findings into the clinical arena.

Research themes in the School

Clinical Cardiovascular Science (CCS)

Description
Cardiovascular Sciences in Birmingham brings together researchers in the School of Clinical and Experimental Medicine with groups in the School of Health and Population Sciences, and in the College of Life Sciences, linked strategically through the Centre for Cardiovascular Sciences. Cellular, molecular and physiological investigations inform translational research on atrial fibrillation, heart failure, thrombosis, inflammatory vascular disease and responses to ischaemia and hypoxia.

Clinical Respiratory Science

Description
Clinical respiratory research in Birmingham centres on inflammatory mechanisms underlying lung injury and fibrosis in disorders including acute lung injury, chronic obstructive pulmonary disease, vasculitis and interstitial lung disease.

Diabetes, Obesity and Metabolism

Description
In the Birmingham Centre for Endocrinology, Diabetes and Metabolism (CEDAM) we are attempting to understand the causes of obesity and diabetes with the aim of identifying new and novel treatment targets that may ultimately make a difference to patients care.

Endocrine Cancer

Description
Within Endocrine Cancer, our research relies on a balance of cutting-edge scientific methodologies and deep clinical understanding of the diseases we are trying to treat. Our internationally-renowned scientific researchers have expertise in the most innovative and cutting-edge techniques.

Inherited Disorders

Description
Our internationally recognised research into inherited diseases covers a range of clinical specialties and scientific disciplines. Thus research may range from identifying novel human disease genes to understanding the function of a human disease gene product to using cellular and model organisms to develop new treatments for inherited diseases.

Neurodegenerative Diseases

Description
Our team works on a wide range of topics relating to acute and chronic neurodegenerative diseases. Current research programmes concern the genetics and cellular pathology of neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, Motor Neurone Disease, Multiple Sclerosis and Glaucoma.

Neurotrauma

Description
The Neurotrauma research group encompasses laboratory scientists, clinicians and biotechnologists who share expertise, knowledge and solutions.

Reproduction, Embryology & Paediatrics

Description
This theme primarily addresses the health and disease processes that effect Women's Health, mother's wellbeing during pregnancy and children, with research spanning the breadth of laboratory based science (such as molecular biology) to translational research in the form of critical appraisal of the literature and interventional trials.

Steroid Hormone Action

Description
Research into steroid hormone action is a flagship area of hormone and metabolism research in Birmingham. Our work has clarified the role of major enzyme systems in the tissue-specific regulation of steroid action, namely of glucocorticoids and sex steroids. We have discovered novel causes of adrenal and gonadal disorders, helping to shed light on very common disorders including obesity, hypertension and polycystic ovary syndrome

Vascular Inflammation, Thrombosis and Angiogenesis

Description
This multidisciplinary research area brings together research in platelet signalling and function, leukocyte trafficking and endothelial cell biology, aiming to alleviate a variety of pathologies including thrombo-inflammatory vascular pathology, platelet function disorders and cancer angiogenesis, with major support from the British Heart Foundation.