Research in the School

ResearchThe School of Clinical and Experimental Medicine focuses on a number of research areas, and provides a coherent management and support structure for these which facilitates cross-disciplinary interactions and clinical access and hence translation of basic research findings into the clinical arena.

Research themes in the School

Cardiorespiratory Integration and Control (CRIC)

Description
The aim of the CRIC theme is to work towards a greater understanding of the physiological and pathological processes underlying the co-ordinated regulation of cardiovascular and respiratory homeostasis in health and disease. The group consists of basic scientists and clinicians from across the University studying the impact of acute and chronic disturbances of oxygen delivery and utilisation.

Clinical Cardiovascular Science

Description
Clinical cardiovascular research in the Centre for Cardiovascular Sciences encompasses a number of active research groups, both from university and NHS staff. These include groups in cardiology, cardiothoracic surgery, primary care and cardiovascular physiology

Clinical Respiratory Sciences

Description
Clinical respiratory research in Birmingham centres on inflammatory mechanisms underlying lung injury and fibrosis in disorders including acute lung injury, chronic obstructive pulmonary disease, vasculitis and interstitial lung disease. Basic science themes include lung epithelial cell biology, the effects of aging upon neutrophil function and local endocrine systems within the lung.

Diabetes, Obesity and Metabolism

Description
In the Birmingham Centre for Endocrinology, Diabetes and Metabolism (CEDAM) we are attempting to understand the causes of obesity and diabetes with the aim of identifying new and novel treatment targets that may ultimately make a difference to patients care.

Endocrine Cancer

Description
Within Endocrine Cancer, our research relies on a balance of cutting-edge scientific methodologies and deep clinical understanding of the diseases we are trying to treat. Our internationally-renowned scientific researchers have expertise in the most innovative and cutting-edge techniques.

Inherited Disorders

Description
Our internationally recognised research into inherited diseases covers a range of clinical specialties and scientific disciplines. Thus research may range from identifying novel human disease genes to understanding the function of a human disease gene product to using cellular and model organisms to develop new treatments for inherited diseases.

Neurotrauma and Neurodegeneration

Description
Information on the Section of Neurotrauma and Neurodegeneration, led by Professor Ann Logan, School of Clinical and Experimental Medicine, The University of Birmingham.

Reproduction, Embryology & Paediatrics

Description
This theme primarily addresses the health and disease processes that effect Women's Health, mother's wellbeing during pregnancy and children, with research spanning the breadth of laboratory based science (such as molecular biology) to translational research in the form of critical appraisal of the literature and interventional trials.

Steroid Hormone Action

Description
Research into steroid hormone action is a flagship area of hormone and metabolism research in Birmingham. Our work has clarified the role of major enzyme systems in the tissue-specific regulation of steroid action, namely of glucocorticoids and sex steroids. We have discovered novel causes of adrenal and gonadal disorders, helping to shed light on very common disorders including obesity, hypertension and polycystic ovary syndrome

Vascular Inflammation, Thrombosis and Angiogenesis (VITA)

Description
The overall aim of the VITA research theme is to understand the events that underlie the interaction of vascular cells with each other and with matrix proteins, and how these change in cardiovascular disorders such as atherosclerosis, arterial thrombosis, cancer growth and metastasis, ischaemia reperfusion injury and chronic vascular inflammation.