Dr Wendy Leadbeater PhD, PGCertLTHE, BSc (Hons)

Lecturer in Medical Sciences

Neurotrauma and Neurodegeneration

Contact details

Telephone +44(0)121 414 4505

Email w.leadbeater@bham.ac.uk

School of Clinical and Experimental Medicine
College of Medical and Dental Sciences
University of Birmingham
Edgbaston
Birmingham
B15 2TT

About

Wendy Leadbeater is a lecturer in the School of Clinical and Experimental Medicine. Wendy has published research papers in the field of neuroscience.  She has a predominant teaching role and due to her interest in education is involved in pedagogical educational research with other members of the college.

Qualifications

  • PGCert in Learning and Teaching in Higher Education 2010
  • Fellowship for Higher Education Academy 2010
  • Awarded Prize of Excellence in PGCertLTHE Part 1 2009
  • PhD Neuroscience 1999
  • BSc (Hons) Cell and Molecular Biology 1992

Biography

Wendy Leadbeater qualified with a first class BSc (Hons) in Cell and Molecular Biology from University of Essex. She went on to study for a PhD in Neuroscience at the University of Birmingham. Wendy worked for three years completing post-doctoral training in Canada in a molecular diabetes laboratory where she received a Canadian Institute of Health Research Fellowship. After receiving a BBSRC post-doctoral fellowship Wendy continued to work in neural repair and regeneration in the Molecular Neuroscience Group at the University of Birmingham. Wendy was awarded a lectureship in Medical Sciences in 2008.

Teaching

  • Module co-ordinator for Biological Sciences 1 and 2 in BMedSc Biomedical Materials Science 1, with responsibility to deliver the neuroscience teaching and assessment.
  • Deputy module co-ordinator for BMedSc3 Neuroscience module with responsibility to deliver lectures, practical sessions and assessment.
  • Tutor across teaching areas which include; cardiovascular, respiratory, renal, digestion, endocrinology, research methods and experimental design across the degree programmes; MBChB1 and 2, BMedSc1 and 2 and BDS1.
  • Facilitator for Integrated Problems, MBChB1.
  • Responsible for the delivery of a student selected activity (SSA) for MBChB.
  • Supervisor for BMedSc3, research student (dissertation).

Postgraduate supervision

  • PhD supervisor
  • Supervisor for MRes programme, research student (dissertation)

Research

As part of the Molecular Neuroscience Group, the research focus is on the evaluation of strategies to deliver gene biotherapeutics to the injured central nervous system (CNS) to better understand the role in scarring and neural regeneration.

Wendy is also interested in learning and teaching scholarship and research, and has published a case study in reviewing scientific literature in the Higher Education Academy, Biosciences subject centre.

Other activities

  • Member of the Biomedical Materials Curriculum Development Committee
  • External lecturer for Coventry University
  • Member of CLAD Board of Studies
  • Member of CLAD Programme Committee
  • Member of Physiological Society Teaching Special Interest Group

Publications

Baird, A., Eliceiri, B., Johanson, C., Stopa, E., Leadbeater W., Gonzalez, AM. 2011. Targeting of the choroid plexus-CSF brain nexus using phage peptides identified by phage display. Book chapter in Methods in Molecular Biology, edited by Su Nag. The Blood-Brain and Other Neural Barriers: Reviews and Protocols. Humana Press. Volume 686, part 5, 483-498.

Ana M Gonzalez, Sonia Podvin, Shuh-Yow Lin, Miles C Miller, Hannah Botfield, Wendy E Leadbeater, Andrew Roberton, Xitong Dang, Stuart E Knowling, Elena Cardenas-Galindo, John E Donahue, Edward G Stopa, Conrad E Johanson, Raul Coimbra, Brian P Eliceiri and Andrew Baird. 2011. Ecrg4 expression and its product augurin in the choroid plexus: impact on fetal brain development, cerebrospinal fluid homeostasis and neuroprogenitor cell response to CNS injury. Fluids and barriers of the CNS 8:6

Gonzalez, AM, Leadbeater, W, Burg, M., Sims, K., Terasaki, T., Johanson, C., Stopa, E., Eliceiri, B., Baird, A. 2011 Targeting Choroid Plexus Epithelia and Ventricular Ependyma in the Central Nervous System. BMC Neuroscience. Jan 7; 12(1), 4

Gonzalez AM, Leadbeater, W., Podvin, S., Borloa, A., Sawada, R., Rayner, J., Sims, K., Terasaki, T., Johanson, C., Stopa, E., Eliceiri, B., Baird, A. 2010. Epidermal Growth Factor Targeting of Bacteriophage to the choroid plexus for gene delivery to the Central Nervous System via Cerebrospinal Fluid. BRES-D-10-00945R1. Brain Research 1359, 1-13.

Gonzalez, A.M., Taylor, W.M., Johanson, C.E., King, J.C., Leadbeater, W.E., Duncan, J.A., Stopa, E.G., Baird, A. 2010. Co-localisation and regulation of basic fibroblast growth factor and arginine vasopressin in neuroendocrine cells of the rat and human brain. Cerebrospinal Fluid Research, 7:13 (13 August 2010) doi:10.1186/1743-8454-7-13

Douglas, M.R., Morrison, K.C., Jacques, S.J., Leadbeater, W.E., Gonzalez, A.M., Berry, M., Logan, A., Ahmed, Z. 2009. Off-target effects of epidermal growth factor receptor antagonists mediate retinal ganglion cell disinhibited axon growth. Brain; 132 (Pt 11), 3102-3121. DOI:10.1093/brain/awp240.

Gonzalez, A.M., Berlanga, O., Leadbeater W.E., Cooper-Charles L., Sims K., Logan A., Eliceiri B., Berry M., Baird A. 2009. The deployment of adenovirus-containing gene activated matrices onto severed axons after CNS injury leads to transgene expression in target neuronal cell bodies. Journal of Gene Medicine 11: 679-688.

Leadbeater W.E., Gonzalez A.M., Logaras N., Berry M., Turnbull.J, Logan A. 2006. Intracellular trafficking in neurons and glia of FGF-2, FGFR1 and heparin sulphate proteoglycans in the injured adult rat cerebral cortex. Journal of Neurochemistry 96(4): 1189-1200

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