Stephen Murphy is a clinical academic based at Birmingham Children’s Hospital NHS Foundation Trust where he has worked as a paediatric gastroenterologist since 1993. His clinical department provides a secondary and tertiary referral service for children with serious and complex gastrointestinal disorders – and the department receives referrals from throughout the West Midlands and well as national and international referrals.
He has an interest in clinical research particularly in the field of inflammatory bowel disorders such as Crohn’s disease. He has published many research papers as well as reviews and textbook chapters in paediatric gastroenterology. He is editor of a textbook on Pediatric Gastrointestinal Endoscopy. He has been closely involved in establishing and developing the Medicines for Children Research Network (MCRN) to support clinical trials in children nationwide.
He has a major interest in Evidence Based Medicine. He was chairman of the guideline development group for NICE Clinical Guideline on gastroenteritis in children. He is Clinical Co-Director (Child Health) at the National Collaborating Centre for Women’s and Children’s Health.
Stephen Murphy qualified in Medicine at the National University of Ireland (University College Cork) in 1977. He trained in paediatrics at the Cork University Hospital, Our Lady’s Hospital for Sick Children in Dublin, the John Radcliffe Hospital in Oxford, Great Ormond Street Hospital in London, and the Royal Victoria Hospital in Newcastle upon Tyne. He was awarded an Action Research Training Fellowship at the University of Newcastle upon Tyne to train as a clinical scientist (1985-1988). He held a Fellowship and subsequently worked as Attending Physician in the Combined Program in Pediatric Gastroenterology & Nutrition (Harvard Medical School, The Children’s Hospital, Massachusetts General Hospital) in Boston, USA (1988-1991). He was appointed Lecturer in Hepatology (Univerity of Birmingham) in 1991 and was appointed to his current post in 1993 – Senior Lecturer in Paediatrics & Child Health and honorary Consultant in Paediatric Gastroenterology.
Stephen Murphy is currently involved in clinical trials and studies in paediatric inflammatory bowel disease:
Chief Investigation for multi-centre randomised controlled trial on the impact of treatment for active Crohn’s disease on bone metabolism and structure
Chief investigator in cohort study on effects of biologic (e.g., infliximab) on the musculoskeletal unit in children with inflammatory bowel disease
Co-investigator in international study on the treatment of osteoporosis in children with inflammatory conditions and receiving steroid therapy
Principle investigator in planned randomised controlled trial on the effects of lipids in parenteral nutrition on cholestatic liver disease
Principle investigator in national paediatric IBD genetics consortium
Visintin C, Mugglestone MA, Fields EJ, Jacklin P, Murphy MS, Pollard AJ; Guideline Development Group; National Institute for Health and Clinical Excellence. Management of bacterial meningitis and meningococcal septicaemia in children and young people: summary of NICE guidance. BMJ. 2010 Jun 28;340:c3209.
Rennie J, Burman-Roy S, Murphy MS; Guideline Development Group. Neonatal jaundice: summary of NICE guidance. BMJ. 2010 May 19;340:c2409.
Wilson D, Thomas A, Croft N, Newby E, Akobeng A, Sawczenko A, Fell J, Murphy MS, Beattie R, Sandhu B, Mitton S; and the IBD Working Group of the British Society of Paediatric Gastroenterology, Hepatology, and Nutrition. Systematic Review of the Evidence Base for the Medical Treatment of Paediatric Inflammatory Bowel Disease. J Pediatr Gastroenterol Nutr. 2010 Jan 13. [Epub ahead of print]
Khanna R, Lakhanpaul M, Burman-Roy S, Murphy MS; Guideline Development Group and the technical team. Diarrhoea and vomiting caused by gastroenteritis in children under 5 years: summary of NICE guidance. BMJ. 2009 Apr 22;338:b1350.
Mossop H, Davies P, Murphy MS. Predicting the need for azathioprine at first presentation in children with inflammatory bowel disease. J Pediatr Gastroenterol Nutr. 2008 Aug;47(2):123-9.
Rodrigues AF, Johnson T, Davies P, Murphy MS. Does polymeric formula improve adherence to liquid diet therapy in children with active Crohn's disease? Arch Dis Child. 2007 Sep;92(9):767-70. Epub 2007 May 2.
Murphy MS. New drugs: kids come first; con: first adults, then children. Inflamm Bowel Dis. 2007 Sep;13(9):1170-5; discussion 1176-7. No abstract available. PMID: 17538986 [PubMed - in process]
Devadason D, Murphy MS, Brown R, Wilson D, McKiernan PJ. Duodenal capillary hemangiomatous polyps: a novel manifestation of extrahepatic portal hypertension? J Pediatr Gastroenterol Nutr. 2007 Jul;45(1):114-6.