Since his appointment as a Clinical Lecturer in Periodontology in 1999, Dr Milward has strived to develop skills in both teaching and research. Mike has a keen interest in enhancing the educational environment for our students, and with this in mind has developed a number of innovative educational approaches, examples include introduction of computer based learning material, development of a Progress File scheme, and introduction of Infection Control Competency tests for undergraduate students. Mike has recently taken on the role of Quality Assurance & Enhancement lead for the School of Dentistry, and has become head of Periodontology Specialty Teaching.
Dr Milward is a calibrated clinical examiner for a number of multi-national companies and is a key member of the clinical trials team based in Periodontology at The School of Dentistry. To date Mike has been involved in 12 clinical trials, with a further study commencing in 2011. These studies have brought in considerable funding to the University and School as well as being published in the scientific literature.
In addition to his clinical trials based research Mike is committed to continuing research aimed at elucidating the mechanisms underpinning the aetiology of periodontitis, which formed the basis of his PhD thesis. In an attempt to achieve this goal he is actively developing a broad range of collaborations and is supervising a number of PhD students with the aim of taking this research work forward.
Dr Milward’s external professional activities include membership of the British Society of Periodontology, where he sits on the Education Committee, which has developed a range of activities aimed at improving the knowledge and management of periodontitis within the dental community. He has also recently taken on the role of Treasurer of this prestigious society.
Dr Milward is currently involved in the following research projects:
(i) Effect of Dietary Supplementation on chronic periodontitis patients (National Safety Associates, USA).
(ii) Is primary Sjogrens Syndrome the consequence of an aberrant immune response to oral bacteria? (University Hospital Birmingham Charities Research Grant).
(iii) Outcomes of Periodontal Therapy in Rheumatoid Arthritis (National Institute for Health Research).
(iv) Gums and Joints – FP 7.0 consortium grant.
(v) FT-ICR MS proteomics in salivary diagnostics (Philips USA).
(vi) A novel device for phototherapy to promote dental tissue repair (National Institute for Health Research i4i grant)
Dr Milward's future plans involve delivering on his current projects but also trying to develop collaborations leading to further successful research grant applications. His current collaborations with researchers at the Medical School have been very fruitful and have added a further dimension to dental and biomedical research. Dr Milward’s clinical / research skills add considerable value to research ideas especially with the current interest in associations with periodontitis and systemic diseases, thereby opening a number of potential areas for research grant funding.
He has recently been involved in developing a new research area of photonics in oral disease, which has recently attracted funding from National Institute for Health Research (i4i) to develop a novel therapeutic based device.
1. Dias IH, Chapple IL, Milward M, Grant MM, Hill E, Brown J, Griffiths HR 2013. Sulforaphane restores cellular glutathione levels and reduces chronic periodontitis neutrophil hyperactivity in vitro.. PLoS One. 8(6)
2. de Pablo P, Dietrich T, Chapple IL, Milward M, Chowdhury M, Charles PJ, Buckley CD, Venables PJ 2013. The autoantibody repertoire in periodontitis: a role in the induction of autoimmunity to citrullinated proteins in rheumatoid arthritis?. Ann Rheum Dis.16.
3. Holder MJ, Milward MR, Palin WM, Hadis MA, Cooper PR 2012. Effects of red light-emitting diode irradiation on dental pulp cells.. J Dent Res. 91(10):961-6.
4. MR Milward, ILC Chapple, K Carter, JB Matthews & PR Cooper 2013. Micronutrient Modulation of NF-kB in Oral Keratinocytes Exposed to Periodontal Bacteria.. Innate Immun. 9(2):140-51.
5. Scott A, Milward MR, Matthews JB, Brock GR, Carlile M, Linden G, Lundy F, Naeeni MA, Kinane DF, Chapple ILC 2012. Mapping biological to clinical pheonotypes during the development (21 days) and resolution (21 days) of experimental gingivitis. J Clin Periodontol. 39(2):123-31
6. Iain L.C Chapple, Michael R. Milward, Nicola Ling-Mountford, Paul Weston, Kevin Carter, Keeley Askey, Gerard E Dallal, John B. Matthews 2012. Adjunctive daily supplementation with encapsulated fruit, vegetable and berry juice powder concentrates and clinical periodontal outcomes: a double blind RCT. J Clin Periodontol. 39(1):62-72
7. Matthews JB, Chen F-M, Wright HJ, Milward MR, Carter K, McDonagh A, Chapple ILC 2011. Respiratory Burst of Neutrophils Stimulated by Fusobacterium nucleatum and IgG-opsonised Staphylococcus aureus is Reduced by Cigarette Smoke Extract. J Clin Periodontol. 38(3):208-18
8. Milward MR, Chapple ILC, Wright HJ, Millard JL, Matthews JB, Cooper PR 2007. Differential activation of NF-kB and gene expression in oral epithelial cells by periodontal pathogens clinical and experimental immunology.. Clinical and Experimental Immunology. 148(2)