The programme is based on a 1 + 3 year model with all students embarking on a bespoke MRes degree in year 1 which will include training in research methods and lectures in inflammation biology, and three rotation projects of which one may be taken in an international research group, such as one of our three strategic partners in Calgary, Illinois and Melbourne. There will also be a group research project. A unique feature of the program is that, following thesis submission, all students will be able to apply for an additional 9 months of funding to complete outstanding publications and/or apply for independent postdoctoral fellowships.
Why study inflammation?
Inflammation is a complex protective response that serves to eliminate the cause of cell injury or infection, as well as removing any necrotic cells and tissues, and initiating the process of repair. The acute inflammatory response involves the migration of leukocytes into the injured tissue along with elevation of a variety of chemokines, cytokines and related mediators, which together are essential for the resolution of infection and damage. However inappropriate inflammation can lead to a variety of inflammatory diseases which range from acute sepsis to chronic inflammatory disorders such as rheumatoid arthritis, asthma and atherosclerosis. A detailed understanding of how to trigger, control, and limit inflammatory responses would open the door to unprecedented medical advances, both in harnessing the host immune system in eradicating infection and in reducing the substantial burden of acute and chronic inflammatory diseases.
Our four-year PhD programme aims to tackle this major healthcare need by training the next generation of inflammation researchers in cross-disciplinary inflammation research, allowing them to move seamlessly from molecular studies (both cellular and subcellular) through whole animal physiology to human clinical trials.
The programme is relevant to students with a good degree (equivalent to first / high 2:1; or distinction in masters programmes) from within the UK / EU with an interest in inflammation-based research including protein structure, cell signalling, cell biology, organ pathology, animal models and clinical studies. It is suitable for students at the interface of the biological and physical scientists with an interest areas such as mathematical modelling and advanced imaging.
Exceptionally, funding may be available for outstanding candidates from other parts of the world: if this applies to you, please contact us in the first instance to discuss this further.