Gillian Grafton qualified with a BSc (Hons) in Biochemistry from King’s College London in 1984. After a brief sojourn as a clinical chemist she went on to study for a PhD in Medicine at the University of Birmingham. From there she went to the MRC Toxicology Unit in Leicester before returning to Birmingham to the Department of Immunology.
While at Birmingham she developed research interests in cellular signalling with a particular emphasis on calcium signalling. She has been an invited speaker at conferences organised by the Keystone Symposia, the British Society for Immunology, the Endocrinology Society and the Biochemical Society and was a regular reviewer for the journal Immunology.
After 14 years at Birmingham she spent some time working in the IT industry and then in the NHS before returning once more. She is currently in the Department of Pharmacology.
Gagro A, Servis D, Cepika A.M., Toellner K.M., Grafton G, Taylor D.R., Branica S., Gordon J. (2006) Type I cytokine profiles of human naïve and memory B lymphocytes: a potential for memory cells to impact polarization Immunology 118 (1): 66-77
Stokes L, Gordon J, Grafton G. (2004) Non-voltage-gated L-type Ca2+ channels in human T cells: pharmacology and molecular characterization of the major a pore-forming and auxiliary b subunits J. Biol. Chem. 279(19):19566-19573 279(19):19566-19573
Grafton G, Stokes L, Toellner K.M., Gordon J. (2003) A non-Voltage-Gated Calcium Channel with L-Type Characteristics Activated by B Cell Receptor Ligation Biochem. Pharmacol. 66: 2001-2009 66: 2001-2009
Serafeim A, Holder M.J., Grafton G, Chamba A, Drayson M.T., Luong Q.T., Bunce C.M., Gregory C.D., Barnes N.B., Gordon J. (2003) Selective serotonin reuptake inhibitors directly signal for apoptosis in biopsy-like Burkitt lymphoma cells. Blood101 (8): 3212-3219
Serafeim A., Grafton G., Chamba A., Gregory C. D., Blakely R. D., Bowery N. G., Barnes N. M., Gordon, J. (2002) 5-Hydroxytryptamine drives apoptosis in biopsy-like Burkitt lymphoma cells: reversal by selective serotonin reuptake inhibitors. Blood 99, 2545-2553.
Challa A., Eliopoulos A. G., Holder M. J., Burguete A. S., Pound J. D., Chamba A., Grafton G., Armitage R. J., Gregory C. D., Martinez-Valdez H., Young L., Gordon J. (2002) Population depletion activates autonomous CD154-dependent survival in biopsy-like Burkitt lymphoma cells. Blood 99, 3411-3418.
Grafton, G., Thwaite L. (2001). Calcium channels in lymphocytes. Immunology 104(2): 119-126. 104(2): 119-126.
Gordon J., Grafton G., Wood P.M., Larché M., Armitage R.J. (2001), Modelling the human immune response: can mice be trusted? Curr. Opin. Pharmacol. 1: 431-435.