Part of the School Seminar Series
Speaker: Professor Richard Wise, CUBRIC, Cardiff University
Most functional MRI studies use blood oxygenation level dependent (BOLD) contrast to qualitatively map 'brain activity'. BOLD fMRI signals can be hard to interpret in studies of drug and disease effects where the underlying state of the brain can be altered. I will discuss complementary approaches to BOLD fMRI and their potential applications. I will explore measurement of cerebral blood flow and cerebrovascular function and how to put numbers to brain activity by measuring cerebral oxygen metabolism.