Dr Charlotte Flavell PhD

Dr Charlotte Flavell

School of Psychology
Postdoctoral Research Fellow

Contact details

Address
School of Psychology
University of Birmingham
Edgbaston
Birmingham
B15 2TT
UK

Dr Charlotte Flavell is a post-doctoral research fellow in the Memory Persistence Lab. She is chiefly interested in the molecular mechanisms associated with memory reconsolidation and the ways that this can be applied to maladaptive memories, such as those associated with PTSD (post traumatic stress disorder) and addiction.

Qualifications

  • BMedSc (University of Birmingham)
  • PhD Neuroscience (University of Bristol)

Biography

Charlotte completed her PhD at the University of Bristol under the supervision of Professor Richard Apps and Professor Bridget Lumb. She subsequently took up a post-doctoral research position in the Memory Persistence Lab at the University of Birmingham, where she currently investigates memory mechanisms of reconsolidation. Charlotte also spent an enjoyable 18 months working in Australia at the Queensland Brain Institute (University of Queensland, Brisbane) with Dr Tim Bredy.

Research

Research interests

  • Neuroscience
  • Learning and Memory
  • Addiction
  • Fear
  • Reconsolidation

Other activities

  • Pint of Science Festival Birmingham 2016 – Coordinator
  • Pint of Science Festival Birmingham 2015 – Coordinator and Event Manager

Publications

“Long noncoding RNA-directed epigenetic regulation of gene expression is associated with anxiety-like behavior in mice” Spadaro, P.A., Flavell, C.R., Widagdo, J., Ratnu, V.S., Troup, M., Ragan, C., Mattick, J.S. & Bredy, T.W. (2015) Biological Psychiatry 78(12):848-59

“Inhibition and enhancement of contextual fear memory destabilization” Lee, J.L. & Flavell, C.R. (2014) Frontiers in Behavioural Neuroscience 8: 144

“Neocortical Tet3-mediated accumulation of 5-hydroxymethylcytosine promotes rapid behavioural adaptation” Li, X., Wei, W., Zhao, Q.Y., Widagdo, J., Baker-Andresen, D., Flavell, C.R., D’Alessio, A., Zhang, Y., & Bredy, T.W. (2014) PNAS 111(19): 7120-5

“Spino-olivary projections are anatomically separate from post synaptic dorsal column projections” Flavell, C.R., Cerminara, N.L., Apps, R. & Lumb, B.M. (2014) Journal of Comparative Neurology 522(9): 2179-90

“Mechanisms governing the reactivation-dependent destabilization of memories and their role in extinction” Flavell, C.R., Lambert , E.A., Winters, B.D., & Bredy, T.W. (2013) Frontiers in Behavioural Neuroscience 7:214

“Reconsolidation and extinction of an appetitive pavlovian memory” Flavell, C.R. & Lee, L.C. (2013) Neurobiology of Learning and Memory 104: 25-31

“The olivocerebellar system and it’s relationship to survival circuits” Watson, T.C., Koutsikou, S., Cerminara, N.L., Flavell, C.R., Crook, J.J. Lumb, B.M. & Apps, R. (2013) Frontiers in Neural Circuits 7:72

“Activation of BDNF signaling prevents return of fear in female mice” Baker-Andresen, D., Flavell, C.R., Li, X. & Bredy, T.W. (2013) Learning and Memory 20: 237-240

“Post-training unilateral amygdala lesions selectively impair contextual fear memories” Flavell, C.R. & Lee, J.L.C. (2012) Learning and Memory 19(6):256-63

“Behavioural memory reconsolidation of food and fear memories”. Flavell, C.R., Barber, D.J. & Lee, J.L.C. (2011) Nature Communications, 2:504 doi: 10.1038/ncomms1515.