Ms Janine Dretzke

Institute of Applied Health Research
Research Fellow/Senior Systematic Reviewer

Contact details

Address
Biostatistics, Evidence Synthesis and Test Evaluation (BESaTE)
Institute of Applied Health Research
College of Medical and Dental Sciences
University of Birmingham
Edgbaston
Birmingham, B15 2TT

Janine has considerable experience in conducting evidence syntheses, meta-analyses, systematic reviews and health technology assessments (HTA) to inform local and national healthcare decision making. She is a team leader for the Birmingham Clinical Trials Unit (BCTU) systematic review team and advises researchers within the NIHR Surgical Reconstruction and Microbiology Research Centre (SRMRC) on systematic review methodology. Janine also teaches and is a module coordinator of the ‘systematic review and evidence synthesis’ module (MPH (HTA)).  

Qualifications

  • MSc Health Technology Assessment (University of Birmingham 2003)
  • MSc Environmental Management (University of Stirling 1996)
  • BSc Biological Sciences with Microbiology (University of Warwick 1995)

Teaching

Research

Evidence syntheses, systematic reviews, health technology assessments

Other activities

Module coordinator for the systematic reviews and evidence synthesis module of the MPH (HTA)

Publications

Smith IM, James RH, Dretzke J, Midwinter MJ. Pre-hospital blood product resuscitation for trauma: a systematic review. Shock. 2016 Jan 22. [Epub ahead of print] 

Stewart SK, Bennett PM, Stapley SA, Dretzke J, Bem D, Penn-Barwell JG. Pre-clinical evaluation of therapies to prevent or treat bone non-union: a systematic review protocol. Syst Rev. 2015 Nov 12;4(1):161. 

Kwei J, Halstead FD, Dretzke J, Oppenheim BA, Moiemen NS. Protocol for a systematic review of quantitative burn wound microbiology in the management of burns patients. Syst Rev. 2015 Nov 6;4:150. 

Dretzke J,  Blissett D, Dave C, Mukherjee R, Price M, Bayliss S, Wu X, Jordan R, Jowett S, Turner A, Moore D. The cost-effectiveness of domiciliary non-invasive ventilation (NIV) in patients with end-stage COPD. A systematic review and economic evaluation. Health Technol Assess 2015; 19 (81) 

Naumann DN, Dretzke J, Hutchings S, Midwinter MJ.  Protocol for a systematic review of the impact of resuscitation fluids on the microcirculation after haemorrhagic shock in animal models. Systematic Reviews  2015;4: 135. 

Bem D, Dretzke J, Stevens S, Lordkipanidzé M, Hodgkinson J, Bayliss S, Moore D, Fitzmaurice D. Investigating the effectiveness of different aspirin dosing regimens and the timing of aspirin intake in primary and secondary prevention of cardiovascular disease: protocol for a systematic review. Systematic Reviews 2015, 4:88 doi:10.1186/s13643-015-0078-3 

Dretzke J, Riley RD, Lordkipanidzé M, Jowett S, O'Donnell J, Ensor J, et al. The prognostic utility of tests of platelet function for the detection of aspirin resistance in patients with established cardiovascular or cerebrovascular disease: a systematic review and economic evaluation. Health Technol Assess 2015;19 (37) 

Chen YF, Bramley G, Unwin G, Hanu-Cernat D, Dretzke J, Moore D, Bayliss S2 Cummins C, Lilford R. Occipital nerve stimulation for chronic migraine - a systematic review and meta-analysis. PLoS One. 2015; 10 (3):e0116786. doi: 10.1371/journal.pone.0116786 

Dretzke J, Ensor J, Bayliss S, Hodgkinson J, Lordkipanidzé M, Richard RD, Fitzmaurice D, Moore D. Methodological issues and recommendations for systematic reviews of prognostic studies: an example from cardiovascular disease. Systematic Reviews 2014, 3:140  doi:10.1186/2046-4053-3-140 

Dave C, Turner A, Dretzke J, Bayliss S, O’Brien D, Jowett S, Moore D. Protocol for a systematic review and economic evaluation of the clinical and cost-effectiveness of non-hospital based non-invasive ventilation (NIV) in patients with stable end stage COPD with hypercapnic respiratory failure; Systematic Reviews 2014; 3:32. doi: 10.1186/2046-4053-3-32. 

Dretzke J, Smith IM, James R, Midwinter MJ. Protocol for a systematic review of the clinical effectiveness of pre-hospital blood components compared to other resuscitative fluids in patients with major traumatic haemorrhage. Systematic Reviews 2014, 3:123  doi:10.1186/2046-4053-3-123 

Dretzke J,  Meadows A, Novielli N, Huissoon A, Fry-Smith A, Meads C. Subcutaneous and sublingual immunotherapy for seasonal allergic rhinitis: A systematic review and indirect comparison. Journal of Allergy & Clinical Immunology 2013; 131(5):1361-6.

Raichand S, Moore D, Riley R, Lordkipanidzé M, Dretzke J, O'Donnell J, Jowett S, Bayliss S and Fitzmaurice D.  Protocol for a systematic review of the diagnostic and prognostic utility of tests currently available for the detection of aspirin resistance in patients with established cardiovascular or cerebrovascular disease. BMC Systematic Reviews 2013, 2:16   

Michelson, D., Davenport, C., Dretzke, J., Barlow, J. & Day, C. Do evidence-based interventions work when tested in the real world? A systematic review and meta-analysis of parent management training for the treatment of child disruptive behaviour. Clinical Child and Family Psychology Review. 2013;16(1):18-34

Meadows A, Kaambwa B, Novielli N, Huissoon A, Fry-Smith A, Meads C, Barton P, Dretzke J. A systematic review and economic evaluation of immunotherapy for seasonal allergic rhinitis. Health Technol Assess.2013;17(27)

Dretzke J, Edlin R, Round J, Connock M, Hulme C, Czeczot J, Fry-Smith A, McCabe C, Meads C. A systematic review and economic evaluation of the use of tumour necrosis factor-alpha (TNF-a) inhibitors, adalimumab and infliximab, for Crohn’s disease. Health Technol Assess 2011;15(6).

Dretzke J, Edlin R, Round J, Connock M, Hulme C, et al. A systematic review and economic evaluation of the use of tumour necrosis factor-alpha (TNF-a) inhibitors, adalimumab and infliximab, for Crohn’s disease. Health Technol Assess 2011;15(6).

Dretzke J, Barton P, Kaambwa B, Connock M, Uthman O, Bayliss S, Meads C. Rituximab for the treatment of relapsed/refractory chronic lymphocytic leukaemia. Health Technol Assess 2010;14(Suppl. 2):19–26

Dretzke J, Round J, Connock M, Tubeuf S, Pennant M, Fry-Smith A, Hulme C, McCabe C, Meads C. Imatinib as adjuvant treatment following resection of KIT-positive gastrointestinal stromal tumours .Health Technol Assess 2010;14(Suppl. 2):63–70

Dretzke J, Davenport C, Frew E, Barlow J, Stewart-Brown S, Bayliss S, Taylor RS, Sandercock J, Hyde C. The clinical effectiveness of different parenting programmes for children with conduct problems: a systematic review of randomised controlled trials. Child Adolesc Psychiatry Ment Health. 2009;3(1):7.

Roberts J, Huissoon A, Dretzke J, Wang D, Hyde C.A systematic review of the clinical effectiveness of acupuncture for allergic rhinitis. BMC Complement Altern Med. 2008;8:13.

Dretzke J, Burls A, Bayliss S, Sandercock J. The clinical effectiveness of pre-hospital intravenous fluid replacement in trauma patients without head injury: a systematic review. Trauma 2006;8:131-141

Dretzke J, Frew E, Davenport C, Barlow J, Stewart-Brown S, Sandercock J, Bayliss S, Raftery J, Hyde C, Taylor R. The effectiveness and cost-effectiveness of parent training/education programmes for the treatment of conduct disorder, including oppositional defiant disorder, in children. Health Technology Assessment 2005; 9 (50)

Dretzke J, Sandercock J, Bayliss S and Burls A. Clinical effectiveness and cost-effectiveness of pre-hospital intravenous fluids in trauma patients. Health Technol Assess 2004;8(23)