Dr Ronan Ryan

Institute of Applied Health Research
Research Fellow

Contact details

Primary Care Clinical Sciences
Institute of Applied Health Research
College of Medical and Dental Sciences
University of Birmingham
B15 2TT

Ronan is particularly interested in the use of electronic patient records for research and has over 10 years’ experience in the use of large primary care databases (CPRD/GPRD, QResearch and THIN).


His longer term aims are:
- to develop and make publicly available appropriate methods that will increase the accessibility and utility of large primary care databases for research; and
- to identify the limits of primary care databases as a data source for clinical studies, in particular for clinical prediction models.


  • PhD in General Practice: Can routinely collected primary care data be used to predict future risk of morbidity and mortality in newly-diagnosed type 2 diabetes mellitus? University of Birmingham, 2012. http://etheses.bham.ac.uk/5397
  • MSc Health Psychology, City University, London, 2000
  • MA Psychology, University College Dublin 1991
  • BA Psychology, University College Dublin, 1990


Prior to being involved in research, Ronan spent about 10 years working in the NHS and for social services as an assistant psychologist and a residential social worker in mental health, learning disabilities, and elderly services.

Since then, he has worked on the General Practice Research Database at the Office for National Statistics, on the QResearch general practice database at the University of Nottingham, and has used The Health Improvement Network (THIN) general practice database for a variety of studies while at the University of Birmingham.


  • Development of clinical prediction models using primary care data.
  • Design and analysis of case-control and cohort studies using primary care data.
  • Analysis of a stepped-wedge randomised control trial to prevent CVD in primary care.
  • Development of a method to impute missing data on ethnicity in cancer registries.


Reeves D, Springate DA, Ashcroft DM, Ryan R, Doran T, Morris R, Olier I, Kontopantelis E. (2014)
Can analyses of electronic patient records be independently and externally validated? The effect of statins on the mortality of patients with ischaemic heart disease: a cohort study with nested case-control analysis.
BMJ Open. 2014 Apr 23;4(4):e004952. doi: 10.1136/bmjopen-2014-004952.

Damery S, Nichols L, Holder R, Ryan R, Wilson S, Warmington S, Stokes-Lampard H, Manavi K. (2013)
Assessing the predictive value of HIV indicator conditions in general practice: a case-control study using the THIN database.
British Journal of General Practice 2013 Jun;63(611):370-7.

Ryan R, Vernon S, Lawrence G, Wilson S. (2012)
Use of name recognition software, census data and multiple imputation to predict missing data on ethnicity: application to cancer registry records.
BMC Medical Informatics & Decision Making 2012 Jan 23;12(1):3.

Damery S, Ryan R, McManus RJ, Warmington S, Draper H, Wilson S on behalf of the Improving Colorectal Outcomes (ICOS) Group. (2011)
The effect of seeking consent on the representativeness of patient cohorts: iron-deficiency anaemia and colorectal cancer.
Colorectal Disease 2011; 13(11):e366-e373.

Damery S, Ryan R, Wilson S, Ismail S, Hobbs FDR. (2011)
Iron deficiency anaemia and delayed diagnosis of colorectal cancer: a retrospective cohort study.
Colorectal Disease 2011; 13: 53-60.

Ryan R, McManus RJ, Mant J, Macleod JA, Hobbs FDR. (2009)
Statins in heart failure: Retrospective cohort study using routine primary care data.
Annals of Medicine 2009; Jun 11:1-7.

Calvert MJ, Shankar A, McManus RJ, Ryan R, Freemantle N. (2009)
Evaluation of the Management of Heart Failure in Primary Care.
Family Practice 2009; 26: 145-153.

McManus R, Ryan R, Jones M, Wilson S, Hobbs FDR. (2008)
How representative of primary care are research active practices?
Family Practice 2008; 25: 56–62.