Thomas L. Clarke, Maria Pilar Sanchez-Bailon, Kelly Chiang, John J. Reynolds, Joaquin Herrero-Ruiz, Tiago M. Bandeiras, Pedro M. Matias, Sarah L. Maslen, J. Mark Skehel, Grant S. Stewart and Clare C. Davies. PRMT5-dependent methylation of the TIP60 coactivator RUVBL1 is a key regulator of homologous recombination. Molecular Cell (published online)
Davies CC, Harvey E, McMahon R, Finegan KG, Connor F, Davies RJ, Tuveson DA, Tournier C (2014) Conditional deletion of mkk4 and mkk7 cooperates with KrasG12D expression to accelerate pancreatic ductal adenocarcinoma in mice. Cancer Research 74 (12), 3344-56.
Davies CC and Behrens A (2013) Arginine methylation: Making its mark on AP-1 gene activation. Cell Cycle 12:15, 2333–2334.
Davies CC, Chakraborty A, Diefenbacher ME, Skehel M, and Behrens A (2013) Arginine methylation of thec-Jun co-activator RACO-1 is required for c-Jun/AP-1 activation. The EMBO Journal 32, 1556 – 1567.
Davies C and Tournier C (2012). Exploring the function of the JNK (c-Jun N-terminal kinase) signalling pathway in physiological processes to design novel therapeutic stratagies. Biochem Soc Trans. (40):85-9.
Knox PG*, Davies CC*, Ioannou M, and Eliopoulos AG (2011). The death domain kinase RIP1 links immunoregulatory CD40 receptor to apoptotic signalling in carcinoma cells. The Journal of Cell Biology,(192):391-399
*Equal contribution to this work.
Davies CC, Chakraborty A, Cipriani F, Haigh K, Haigh JJ and Behrens A (2010). RACO-1 links AP-1 activity to growth factor signalling. Nature Cell Biology, (10): 963-72
*Signalling Gatway Featured Article of the Week
Davies CC, Mak TW, Young LS, Eliopoulos AG (2005). TRAF6 is required for TRAF2 dependent CD40 signal transduction in nonhemopoietic cells. Mol. Cell Biol. (25): 9806-19
Davies CC, Bem D, Young LS, Eliopoulos AG (2005). NF-kB overrides the apoptotic program of TNF receptor 1 but not CD40 in carcinoma cells. Cell Signal (17): 723-38
Davies CC, Mason J, Wakelam MJ, Young LS, Eliopoulos AG (2004). Inhibition of PI3K and ERK MAPK-regulated protein synthesis reveals the pro-apoptotic properties of CD40 ligation in carcinoma cells. J Biol Chem. (279): 1010-19
Eliopoulos AG, Davies C, Blake SS, Murray P, Najafipour S, Tsichlis PN, Young LS (2002). The oncogenic protein kinase Tpl-2/Cot contributes to Epstein-Barr virus-encoded latent infection membrane protein 1-induced NF-kappaB signaling downstream of TRAF2. J Virol. (76):4567-79.
Eliopoulos AG, Davies C, Knox PG, Gallagher NJ, Afford SC, Adams DH, Young LS (2000). CD40 induces apoptosis in carcinoma cells through activation of cytotoxic ligands of the tumor necrosis factor superfamily. Mol Cell Biol. (20):5503-15.