Paul completed a PhD in 1996 under the supervision of Professor Lawrence Young. He was awarded a prestigious Fulbright Fellowship to undertake research at the Johns Hopkins University in Baltimore, working in the laboratories of Professor Richard Ambinder who at the time was pioneering work on the Epstein-Barr virus, a common virus which had, only a few years before, been suggested to be a causative agent in the development of Hodgkin’s lymphoma.
In 2000 Paul came back to the University of Birmingham taking up a senior lectureship in Pathology and established his own research group. In 2005 Paul moved to the Institute for Cancer Studies as Reader in Molecular Pathology. In 2007, Paul was appointed to the Chair of Molecular Pathology in the School of Cancer Sciences.