Dr Christina Yap is a Principal Biostatistician at Cancer Research UK Clinical Trials Unit (CRCTU), within the Institute of Cancer and Genomic Sciences. Her main expertise comprises of development and practical implementation of efficient designs in clinical trials. This includes innovative adaptive designs in early phase dose-finding trials, joint evaluation of safety and activity and randomized Phase II selection designs; as well as late-phase randomised (multi-stage) Phase II/III trials. Her other key areas of expertise include Bayesian designs and analysis in clinical trial and joint modelling of quality of life and survival.
She is the statistical lead for trials in various disease areas, which includes liver, head and neck, skin and leukaemia within the trials unit.