Recent publications
Article
Lim, A, Laskar, S, Steuer, C, Chow, VLY, Szturz, P, Henson, C, Day, AT, Bates, JE, Lazarakis, S, McDowell, L, Mehanna, H & Yom, SS 2024, 'Assessment of endpoint definitions in recurrent and metastatic mucosal head and neck squamous cell carcinoma trials: HNCIG international consensus recommendations', The Lancet Oncology.
Lim, AM, McDowell, L, Hurt, C, Tourneau, CL, Homma, A, Shenouda, G, Thompson, DJ, Moya-Plana, A, Henson, C, Szturz, P, Day, AT, Bates, JE, Lazarakis, S, Thariat, J, Psyrri, A, Mehanna, H & Yom, SS 2024, 'Clinical trial endpoint use and definitions in curative-intent trials for mucosal head and neck squamous cell carcinomas: HNCIG international consensus recommendations.', The Lancet Oncology.
Mehanna, H, Gaunt, P, Kong, A, Hartley, A, Sanghera, P, Forster, M, Sen, M, Paleri, V, Fong, C, Geropantas, D, Srinivasan, D, Garikipati, S, Moleron, R, Casswell, G, Aynsley, E, Ward, A, O'Toole, L, Mirza, A, Firth, C, Humphreys, I, Fulton-Lieuw, T & Nankivell, P 2024, 'CompARE: study protocol for a phase III randomised controlled platform trial comparing alternative regimens for escalating treatment of intermediate and high-risk oropharyngeal cancer', Trials, vol. 25, 50. https://doi.org/10.1186/s13063-023-07881-1
Henson, C, Abou-Foul, A, Glastonbury, C, Huang, SH, King, A, Lydiatt, W, McDowell, LJ, Nagelschneider, AA, Nankivell, P, O'Sullivan, B, Rhys, R, Xiao, Y, Yu, E, Yom, SS & Mehanna, H 2024, 'Criteria for the Diagnosis of Extranodal Extension Detected on Radiological Imaging in Head and Neck Cancer: HNCIG International Consensus Recommendations', International Journal of Radiation: Oncology - Biology - Physics , vol. 118, no. 5, pp. e12-e13. https://doi.org/10.1016/j.ijrobp.2024.01.033
Henson, C, Abou-Foul, A, Glastonbury, C, Huang, SH, King, AD, Lydiatt, WM, McDowell, L, Nagelschneider, AA, Nankivell, P, O'Sullivan, B, Rhys, R, Xiao, Y, Yu, E, Andrew, D, Asmussen, JT, Bidault, F, Dankbaar, JW, de Graaf, P, Gebrim, ES, Hu, C, Ding, J, Kanda, T, Kim, J, Kuno, H, Medrano-Martorell, S, Oikonomopoulos, N, Park-Nam Goh, J, Santos-Armentia, E, Schafigh, DG, Subramaniam, RM, Wu, X, Yom, SS & Mehanna, H 2024, 'Criteria for the diagnosis of extra nodal extension detected on radiological imaging in head and neck cancer: HNCIG international consensus recommendations', The Lancet Oncology.
Mehanna, H, Rapozo, D, Zeidler, SVV, Harrington, K, Winter, S, Hartley, A, Nankivell, P, Schache, A, Sloan, P, Odell, E, Thavaraj, S, Hunter, K, Shah, K, Thomas, G, Long, A, Amel-Kashipaz, R, Brown, R, Conn, B, Hall, G, Matthews, P, Weir, J, Yeo, Y, Pring, M, West, C, McCaul, J, Golusinski, P, Sitch, A, Spruce, R, Batis, N, Bryant, J, Brooks, J, Jones, TM, Buffa, F, Haider, S & Robinson, M 2024, 'Developing and validating a multivariable prognostic-predictive classifier for treatment escalation of oropharyngeal squamous cell carcinoma: the PREDICTR-OPC study', Clinical Cancer Research, vol. 30, no. 2, pp. 356–367. https://doi.org/10.1158/1078-0432.CCR-23-1013
Matheson, L, Greaves, C, Duda, JL, Wells, M, Secher, D, Rhodes, P, Lorenc, A, Jepson, M, Ozakinci, G, Watson, E, Fulton-Lieuw, T, Mittal, S, Main, B, Nankivell, P, Mehanna, H & Brett, J 2024, 'Development of the ‘ACT now & check-it-out’ intervention to support patient-initiated follow up for Head and Neck cancer patients', Patient Education and Counseling, vol. 119, 108033. https://doi.org/10.1016/j.pec.2023.108033
Baliga, S, Abou-Foul, A, Parente, P, Szturz, P, Thariat, J, Shreenivas, A, Nankivell, P, Bertolini, F, Blau, J, Blakaj, D, Brennan, S, Brunet, A, Bueno De Oliveira, T, Burtness, B, Carral Maseda, A, Chow, VLY, Chua, M, de Ridder, M, Garikipati, S, Hanai, N, Ho, F, Huang, SH, Kiyota, N, Klinghammer, K, Kowalski, LP, Kwong, DLW, McDowell, L, Merlano, MC, Nair, S, Economopoulou, P, Overgaard, J, Psyrri, A, Tribius, S, Waldron, J, Yom, SS & Mehanna, H 2024, 'Essential data variables for a minimum dataset for head and neck cancer trials and clinical research: HNCIG consensus recommendations and database', European Journal of Cancer. <https://api.jst.scifree.se/links/birmingham:j:65ba737cdcdeb100011e8c5c>
Patel, A, Brock, K, Slade, D, Gaunt, C, Kong, A, Mehanna, H, Billingham, L & Gaunt, P 2024, 'Implementing the time-to-event continual reassessment method in the presence of partial orders in a phase I head and neck cancer trial', BMC Medical Research Methodology, vol. 24, no. 1, 11. https://doi.org/10.1186/s12874-024-02142-4
Kong, A, Kirkham, AJ, Savage, JS, Mant, R, Lax, S, Good, J, Forster, MD, Sacco, JJ, Schipani, S, Harrington, KJ, Yap, C & Mehanna, H 2024, 'Results and lessons learnt from the WISTERIA phase I trial combining AZD1775 with cisplatin pre- or post-operatively in head and neck cancer', BJC Reports, vol. 2, no. 1, 6. https://doi.org/10.1038/s44276-023-00026-6
Abou-Foul, A, Henson, C, Robinson, M, Chernock, RD, Huang, SH, Lydiatt, WM, Mcdowell, L, O'Sullivan, B, Perez-Ordonez, B, Nankivell, P, Ruiz-Bravo, E, Chiosea, S, McGreen, TM, Hunter, KD, Hwang, JSG, Koljenovic, S, Koppes, SA, Larsen, SR, Lo, AW, Costes-Martineau, V, Mittal, N, Mori, T, Panayiotides, IG, Pinto, CAL, Scheckenbach, K, Seethala, RR, Ulhøi, BP, Vingiani, A, Zhang, Y, Yam, SS & Mehanna, H 2024, 'Standardised definitions and diagnostic criteria for extra nodal extension on histopathological examination in head and neck cancer: HNCIG international consensus recommendations', The Lancet Oncology. <https://www.thelancet.com/journals/lanonc/issue/current>
Ferris, RL, Mehanna, H, Schoenfeld, JD, Tahara, M, Yom, SS, Haddad, RI, König, A, Salmio, S, Bajars, M & Tourneau, CL 2024, 'XRay Vision: A Phase 3 Study of Xevinapant Plus Radiotherapy (RT) for High-risk, Cisplatin-ineligible Patients with Resected, Locally Advanced Squamous Cell Carcinoma of the Head and Neck (LA SCCHN)', International Journal of Radiation: Oncology - Biology - Physics , vol. 118, no. 5, pp. e17-e18. https://doi.org/10.1016/j.ijrobp.2024.01.042
Cavalieri, S, Vener, C, LeBlanc, M, Lopez-Perez, L, Fico, G, Resteghini, C, Monzani, D, Marton, G, Pravettoni, G, Moreira-Soares, M, Filippidou, DE, Almeida, A, Bilbao, A, Mehanna, H, Singer, S, Thomas, S, Lacerenza, L, Manfuso, A, Copelli, C, Mercalli, F, Frigessi, A, Martinelli, E, Licitra, L, BD4QoL Consortium & Nankivell, P 2023, 'A multicenter randomized trial for quality of life evaluation by noninvasive intelligent tools during post-curative treatment follow-up for head and neck cancer: clinical study protocol', Frontiers in Oncology, vol. 13, 1048593. https://doi.org/10.3389/fonc.2023.1048593
Preprint
Shephard, AJ, Bashir, RMS, Mahmood, H, Jahanifar, M, Minhas, F, Raza, SEA, McCombe, KD, Craig, SG, James, J, Brooks, J, Nankivell, P, Mehanna, H, Khurram, SA & Rajpoot, NM 2023 'A Fully Automated and Explainable Algorithm for the Prediction of Malignant Transformation in Oral Epithelial Dysplasia'.
Review article
Ferris, RL, Mehanna, H, Schoenfeld, JD, Tahara, M, Yom, SS, Haddad, R, König, A, Witzler, P, Bajars, M & Tourneau, CL 2024, 'Xevinapant plus radiotherapy in resected, high-risk, cisplatin-ineligible LA SCCHN: the phase III XRay Vision study design', Future Oncology. https://doi.org/10.2217/fon-2023-0774
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