Recent publications
Article
Ronson, GE, Starowicz, K, Anthony, EJ, Piberger, AL, Clarke, LC, Garvin, AJ, Beggs, AD, Whalley, CM, Edmonds, MJ, Beesley, JFJ & Morris, JR 2023, 'Mechanisms of synthetic lethality between BRCA1/2 and 53BP1 deficiencies and DNA polymerase theta targeting', Nature Communications, vol. 14, no. 1, 7834. https://doi.org/10.1038/s41467-023-43677-2
Rana, M, Perotti, A, Bisset, LM, Smith, JD, Lamden, E, Khan, Z, Ismail, MK, Ellis, K, Armstrong, KA, Hodder, SL, Bertoli, C, Meneguello, L, de Bruin, RAM, Morris, JR, Romero-Canelon, I, Tucker, JHR & Hodges, NJ 2022, 'A ferrocene-containing nucleoside analogue targets DNA replication in pancreatic cancer cells', Metallomics, vol. 14, no. 7, mfac041. https://doi.org/10.1093/mtomcs/mfac041
Faulkner, E, Pike, J, Densham, R, Garlick, E, Thomas, S, Neely, R & Morris, J 2022, 'Imaging nanoscale nuclear structures with expansion microscopy', Journal of Cell Science, vol. 135, no. 14, jcs259009. https://doi.org/10.1242/jcs.259009
Garvin, AJ, Lanz, AJ & Morris, JR 2022, 'SUMO monoclonal antibodies vary in sensitivity, specificity, and ability to detect types of SUMO conjugate', Scientific Reports, vol. 12, no. 1, 21343. https://doi.org/10.1038/s41598-022-25665-6
Piberger, L, Bowry, A, Kelly, R, Walker, A, Gonzalez-Acosta, D, Bailey, L, Doherty, A, Mendez, J, Morris, J, Bryant, HE & Petermann, E 2020, 'PrimPol-dependent single-stranded gap formation mediates homologous recombination at bulky DNA adducts', Nature Communications, vol. 11, no. 1, 5863. https://doi.org/10.1038/s41467-020-19570-7
Daza-martin, M, Densham, RM & Morris, JR 2019, 'BRCA1-BARD1: the importance of being in shape', Molecular and Cellular Oncology, vol. 6, no. 6, e1656500. https://doi.org/10.1080/23723556.2019.1656500
Garvin, AJ, Khalaf, AHA, Rettino, A, Xicluna, J, Butler, L, Morris, JR, Heery, DM & Clarke, NM 2019, 'GSK3-SCFFBXW7 mediated phosphorylation and ubiquitination of IRF1 are required for its transcription-dependent turnover', Nucleic Acids Research, vol. 47, no. 9, pp. 4476-4494. https://doi.org/10.1093/nar/gkz163
Daza-Martin, M, Starowicz, K, Jamshad, M, Tye, S, Ronson, GE, MacKay, HL, Chauhan, AS, Walker, AK, Stone, HR, Beesley, JFJ, Coles, JL, Garvin, AJ, Stewart, GS, McCorvie, TJ, Zhang, X, Densham, RM & Morris, JR 2019, 'Isomerization of BRCA1-BARD1 promotes replication fork protection', Nature, vol. 571, no. 7766, pp. 521-527. https://doi.org/10.1038/s41586-019-1363-4
Garvin, AJ, Walker, AK, Densham, RM, Chauhan, AS, Stone, HR, Mackay, HL, Jamshad, M, Starowicz, K, Daza-Martin, M, Ronson, GE, Lanz, AJ, Beesley, JF & Morris, JR 2019, 'The deSUMOylase SENP2 coordinates homologous recombination and nonhomologous end joining by independent mechanisms', Genes & Development, vol. 33, no. 5-6, pp. 333-347. https://doi.org/10.1101/gad.321125.118
Spiliotopoulos, A, Blokpoel Ferreras, L, Densham, RM, Caulton, SG, Maddison, BC, Morris, JR, Dixon, JE, Gough, KC & Dreveny, I 2018, 'Discovery of peptide ligands targeting a specific ubiquitin-like domain-binding site in the deubiquitinase USP11', Journal of Biological Chemistry. https://doi.org/10.1074/jbc.RA118.004469
Uckelmann, M, Densham, RM, Baas, R, Winterwerp, HHK, Fish, A, Sixma, TK & Morris, JR 2018, 'USP48 restrains resection by site-specific cleavage of the BRCA1 ubiquitin mark from H2A', Nature Communications, vol. 9, no. 1, 229. https://doi.org/10.1038/s41467-017-02653-3
Comment/debate
Morris, JR 2021, 'Is it a wrap? Nucleosome interactions of the BRCA1-binding partner, BARD1, steal the scene', Nature Structural and Molecular Biology, vol. 28, no. 9, pp. 708-710. https://doi.org/10.1038/s41594-021-00658-7
Preprint
Faulkner, EL, Pike, JA, Densham, RM, Garlick, E, Thomas, SG, Neely, RK & Morris, JR 2021 'Imaging nanoscale nuclear structures with expansion microscopy' bioRxiv. https://doi.org/10.1101/2021.05.04.442164
Review article
Tye, S, Ronson, G & Morris, J 2021, 'A fork in the road: Where homologous recombination and stalled replication fork protection part ways', Seminars in Cell and Developmental Biology, vol. 113, pp. 14-26. https://doi.org/10.1016/j.semcdb.2020.07.004
Densham, RM & Morris, JR 2019, 'Moving Mountains-The BRCA1 Promotion of DNA Resection', Frontiers in Molecular Bioscience, vol. 6, 79. https://doi.org/10.3389/fmolb.2019.00079
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