Dr Dipak Kotecha

Dr Dipak Kotecha

Institute of Cardiovascular Sciences
NIHR Clinical Lecturer in Cardiovascular Medicine

Contact details

Institute of Cardiovascular Sciences
College of Medical and Dental Sciences
University of Birmingham
B15 2TT

Dipak is a Clinical Lecturer in Cardiovascular Medicine across the clinical sites attached to the University of Birmingham. He is also an Honorary Research Fellow at the Clinical Trials & Evaluation Unit, Royal Brompton Hospital / Imperial College, London and the Monash Centre of Cardiovascular Research & Education, Monash University, Melbourne.

Dipak is also Principal Investigator of the Alternative Risk Markers in Coronary Artery Disease (ARM-CAD) Study (www.armcad.com)

His main interests are vascular function, coronary artery disease and heart failure. He regularly presents at major international conferences and is currently coordinating a global collaborative heart failure group. His teaching interests include clinical echocardiography and biomedical statistics.


  • MBChB 2000
  • MRCP 2004
  • PhD 2010


Dipak studied Medicine at the University of Bristol and trained as a junior doctor in the south-west of England. After gaining Membership of the Royal College of Physicians (London) in 2004 he departed for Australia to gain further clinical and academic experience. He worked as a Cardiology Registrar in Melbourne for 2 years before starting his PhD studies. Registered at the National Heart & Lung Institute, Imperial College London, the PhD was an international collaborative project with Monash University in Melbourne. After completing his PhD, Dipak re-joined the NHS in 2009 and has been a clinical trainee in Oxford. During this time he has continued his academic work, leading to his appointment as a Clinical Lecturer here in Birmingham.


  • Biostatistics tutor, Monash University, Melbourne
  • MRCP PACES tutor, Oxford Deanery
  • Clinical tutor in transthoracic and transoesphageal echocardiography, Oxford Deanery

Postgraduate supervision

  • Supervision of Honours students, Imperial College, London and Monash University, Melbourne.
  • Supervision of research fellows, Oxford.


Principal Investigator of the Alternative Risk Markers in Coronary Artery Disease (ARM-CAD) Study. Multi-centre research study to assess vascular dysfunction and angiographic coronary artery disease in high-risk populations. Secondary data analyses ongoing, including new concepts in arterial pressure compliance, pulse wave velocity measurements, 5-year follow-up data and assessment of biomarkers. (www.armcad.com)

Co-ordinator and steering committee member for the Beta Blockers in Heart Failure Collaborative Group (BB-meta-HF). Establishing a collaboration of global investigators involved in the major trials of beta-blockers in symptomatic left-ventricular dysfunction and undertaking a meta-analysis of individual patient data (n=18630). Currently in data-acquisition and analysis stage.

Principal Investigator of the Cardiovascular Longitudinal Evaluation & Assessment of Risk (CLEAR) Database. Cross-research database to incorporate current and future investigator-driven studies, improve data collection, standardise cardiovascular risk information and enhance recruitment into research projects. Commenced recruitment 2007 (currently n=4500).

Member of the authorship team for a Cochrane Review of erythropoiesis-stimulating agents for anaemia in chronic heart failure patients. Meta-analysis to assess the clinical benefits in terms of exercise tolerance, symptoms, quality of life and health outcomes. Initial Cochrane review publication Jan 2010.

Other activities

  • Cardiology Registrar at the Queen Elizabeth Hospital, Birmingham (specialising in cardiac imaging)
  • Member of the European Society of Cardiology Task Force on Gender


Kotecha D, Piccini JP. Atrial fibrillation in heart failure: what should we do? Eur Heart J. 2015;10.1093/eurheartj/ehv513   http://eurheartj.oxfordjournals.org/content/early/2015/09/28/eurheartj.ehv513.long

Ziff OJ, Lane DA, Samra M, Griffith M, Kirchhof P, Lip GY, Steeds RP, Townend J, Kotecha D. Safety and efficacy of digoxin: systematic review and meta-analysis of observational and controlled trial data. BMJ. 2015;351:h4451

Kotecha D*, Manzano L, Altman DG, Krum H, Erdem G, Williams N, Flather MD. Individual Patient Data Meta-Analysis of Beta-Blockers in Heart Failure: Rationale and Design. Syst Rev 2013;2:7.

Kotecha D*, New G, Collins P, Eccleston D, Krum H, Pepper J, Flather MD.  Radial Artery Pulse Wave Analysis for Non-invasive Assessment of Coronary Artery Disease. Int J Cardiol 2012 (in-press). DOI: http://dx.doi.org/10.1016/j.ijcard.2012.03.098

Kotecha D*, New G, Flather M, Eccleston D, Pepper J, Krum H. Five-minute heart rate variability can predict obstructive angiographic coronary disease. Heart 2012;98:395-401.

Kotecha D*, Ngo K, Walters J, Manzano L, Palazzuoli A, Flather M. Erythropoietin as a treatment of anemia in heart failure: Systematic review of randomized trials. Am Heart J. 2011:161:822-831.

Kotecha D*, Flather M, McGrady M, Pepper J, New G, Krum H, Eccleston D. Contemporary predictors of coronary artery disease in patients referred for angiography. Eur J Cardiovasc Prev Rehabil. 2010:17: 280-288.

Ngo K*, Kotecha D, Walters JA, Manzano L, Palazzuoli A, van Veldhuisen DJ, Flather M. Erythropoiesis-stimulating agents for anaemia in chronic heart failure patients. Cochrane Database Syst Rev. 2010:(1): CD007613.

Cohen-Solal A, Kotecha D*, van Veldhuisen D, Bohm M, Coats A, Roughton M, Babalis D, Poole-Wilson P, Tavazzi L, Flather M. Efficacy & safety of nebivolol in elderly heart failure patients with impaired renal function. Eur J Heart Fail. 2009;11(9):872-80.