Mr Antonio Belli MD, FRCS, FRCS (SN)

 

Professor of Trauma Neurosurgery

Neurobiology

Belli,-Tony-Cropped-110x146

Contact details

Telephone +44 (0) 121 414 4497

Fax +44 (0) 121 414 8867

Email a.belli@bham.ac.uk

School of Clinical and Experimental Medicine
College of Medical and Dental Sciences
Institute of Biomedical Research (West), Room WX 2.61
University of Birmingham
Edgbaston
Birmingham
B15 2TT
UK

About

Mr Belli graduated from Tor Vergata University in Rome with a degree in Medicine and Surgery. He completed a doctoral degree (MD) on neurobiochemistry of brain ischaemia and reperfusion at Tor Vergata University and then moved to the UK in 1994.

He trained as a neurosurgeon at King’s College Hospital, Atkinson Morley’s Hospital, The National Hospital for Neurology and Neurosurgery, Great Ormond Street Hospital, The Royal Free Hospital and Charing Cross Hospital. Between 2001 and 2003 he carried out a research fellowship in neuromonitoring at the Institute of Neurology in London.

He is on the editorial board several neurology journals and is an advisor to NICE and the Care Quality Commission.

Antonio Belli is Director of the NIHR SRMRC.  Find out more about the work of the research centre on the SRMRC website.

Qualifications

  • FRCS (SN)
  • FRCS
  • MD

Biography

Mr Belli is a Professor of Trauma Neurosurgery and Director of the Surgical Reconstruction and Microbiology Research Centre (SRMCR) based at the Queen Elizabeth Hospital Birmingham (http://www.srmrc.nihr.ac.uk/). The SRMRC is a leading centre for trauma research and was founded in 2011 with £20M grant from NIHR, MoD, the University of Birmingham and University Hospitals Birmingham. He heads the neurotrauma research theme, which carries out translational research on traumatic brain injury and spinal cord injury. He is also a practising neurosurgeon at the Queen Elizabeth Hospital where he leads the Neurotrauma service comprised of a formidable team of doctors, nurses and therapists.

Research

Mr Belli’s research interest is in neurobiochemistry and neuromonitoring of acute brain injury. A particular focus is brain metabolism following mild and severe traumatic brain injury and how this relates to the long-term outcome and the risk of early neurogenerative conditions. Many of his current studies involve cross-disciplinary collaborations with engineering, chemistry, computing science and IT.

Working with cerebral microdialysis, another area of interest is early markers of tissue damage for the prevention of secondary injury after trauma and subarachnoid haemorrhage, patient stratification and drug discovery.

He is the principal or chief investigator of several acute brain injury studies, including international multicentre trials.

Other activities

  • Director of NIHR Surgical Reconstruction and Microbiology Research Centre
  • Head of the Neurotrauma theme of NIHR Surgical Reconstruction and Microbiology Research Centre
  • Trustee for Headway West Midlands
  • Module Editor for Neurosurgery for eLearning for Health Care (Royal College of Surgeons of England and Department of Health)
  • Member of the Trauma Group of the British Society of Neurological Surgeons
  • Clinical Advisor to Care Quality Commission Faculty member of the Neurotrauma course at the Royal College of Surgeons of England

Publications

Di Pietro V, Amorini AM, Lazzarino G, Yakoub KM, D'Urso S, Lazzarino G and Belli A (2015) S100B and Glial Fibrillary Acidic Protein as Indexes to Monitor Damage Severity in an In Vitro Model of Traumatic Brain Injury. Neurochem Res 40(5):991-9

Davies DJ, Su Z, Clancy MT, Lucas SJ, Dehghani H, Logan A and Belli A (2015) Near-Infrared Spectroscopy in the Monitoring of Adult Traumatic Brain Injury: A Review. J Neurotrauma [Epub ahead of print]

Lord JM, Midwinter MJ, Chen YF, Belli A, Brohi K, Kovacs EJ, Koenderman L, Kubes P and Lilford RJ (2014) The systemic immune response to trauma: an overview of pathophysiology and treatment. Lancet 384(9952):1455-65

El Ghoul W, Harrisson S and Belli A. (2014) Autologous cranioplasty following decompressive craniectomy in the trauma setting. Br J Neurosurg 6:1-6 [Epub ahead of print]

Stover JF, Belli A, Boret H, Bulters D, Sahuquillo J, Schmutzhard E, Zavala E, Ungerstedt U, Schinzel R and Tegtmeier F; NOSTRA Investigators (2014) Nitric oxide synthase inhibition with the antipterin VAS203 improves outcome in moderate and severe traumatic brain injury: a placebo-controlled randomized Phase IIa trial (NOSTRA). J Neurotrauma 31(19):1599-606

Bulstrode H, Nicoll JA, Hudson G, Chinnery PF, Di Pietro V and Belli A (2014) Mitochondrial DNA and traumatic brain injury. Ann Neurol 75(2):186-95

Di Pietro V, Amorini AM, Tavazzi B, Vagnozzi R, Logan A, Lazzarino G, Signoretti S, Lazzarino G and Belli A (2014) The molecular mechanisms affecting N-acetylaspartate homeostasis following experimental graded traumatic brain injury. Mol Med 20:147-57

Di Pietro V, Lazzarino G, Amorini AM, Tavazzi B, D'Urso S, Longo S, Vagnozzi R, Signoretti S, Clementi E, Giardina B, Lazzarino G and Belli A (2014) Neuroglobin expression and oxidant/antioxidant balance after graded traumatic brain injury in the rat. Free Radic Biol Med 69:258-64

Back to top