Dr Ben Scheven has a long-term track record in the cell biology of hard tissues. Before he was appointed lecturer in at the University of Birmingham, Dr Scheven worked as a research scientist at different institutions in the Netherlands and the UK. His previous research focused on various aspects of bone growth and metabolism with special emphasis on cell differentiation and the role of hormonal and growth factors in development and ageing, health and disease. He has extensive research experience in the development and application of tissue and cell culture models and bioassays to study cellular proliferation, differentiation and function. Dr Scheven has published a range of papers in international peer-reviewed journals.
Current research interests include dental pulp and bone biology, tissue repair and regeneration, mesenchymal and neuronal stem cell differentiation, therapeutic ultrasound and oral cancer.
After Dr Scheven completed his PhD study on the radiosensitivity of long bones and osteoclast development at the Laboratory of Cell Biology and Histology, Medical Faculty of the University of Leiden (The Netherlands), he moved to Aberdeen (Scotland, UK) to work at the Rowett Research Institute, where he further developed his research interests in the regulation of bone metabolism. Subsequently, Dr Scheven worked as senior scientist / research fellow at the Medical Faculty of the University of Utrecht (1989-1994), the Rowett Research Institute (1989-1999) and the University of Aberdeen (1999-2002). Dr. Scheven was also a senior scientist at a Dundee-based, university-spinout, biotechnology company (2002-2005). He took up appointment as lecturer in Oral Cell Biology at the School of Dentistry of the University of Birmingham in January 2006.
Z Gale, PR Cooper, BA Scheven (2011) Effects of glial cell line-derived neurotrophic factor on dental pulp cells. J Dental Res 90: 1240-1245.
Smith AJ, Scheven BA, Takahashi Y, Ferracane JL, Shelton RM, Cooper PR (2011) Dentine as a bioactive extracellular matrix. Arch Oral Biol (Epub, Aug 17].
Scheven BAA (2011) Perceived relevance of oral biology by dental students. Eur J Dent Edu 15:1-9 (http://onlinelibrary.wiley.com/doi/10.1111/j.1600-0579.2011.00677.x/abstract).
Scheven BAA, Shelton RM, Cooper PR, Walmsley AD, Smith AJ (2009) Therapeutic ultrasound for dental tissue repair. Med Hypoth 73: 591–593.
Scheven BA, Man J, Millard JL, Cooper PR, Lea SC, Walmsley AD, Smith AJ (2009) VEGF and odontoblast-like cells: Stimulation by low frequency ultrasound. Arch Oral Biol 54: 185 – 191.
Scheven BA, Millard JL, Cooper PR, Lea SC, Walmsley AD, Smith AJ (2007) Short-term in vitro effects of low frequency ultrasound on odontoblast-like cells. Ultrasound Med Biol 33:1475-1482.
Scheven BAA, Marshall D, Aspden RM (2002) In vitro behaviour of human osteoblasts on dentin and bone. Cell Biol. Int. 26:337-346.
Aspden RM, Scheven BAA, Hutchison JD (2001) Generalised osteoarthritis is a systemic disorder involving stromal cell differentiation and lipid metabolism. Lancet 357:1118-1120.
Scheven BAA, Milne JS, Hunter I, Robins SP (1999) Macrophage-inflammatory protein-1a regulates pre-osteoclast differentiation in vitro. Biochem Biophys Res Commun 254: 773-778.
Scheven BAA, Milne JS, Robins SP (1998) A sequential culture approach to study osteoclast differentiation from non-adherent porcine bone marrow cells. In Vitro Cell Dev Biol 34:568-577.