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ACTIVE Consortium, Schranz, P, Mandalia, V & O’brien, S 2023, 'A randomized trial of autologous chondrocyte implantation versus alternative forms of surgical cartilage management in patients with a failed primary treatment for chondral or osteochondral defects in the knee', American Journal of Sports Medicine, vol. 51, no. 2, pp. 367-378. https://doi.org/10.1177/03635465221141907
Horne, AW, Tong, S, Moakes, C, Middleton, L, Duncan, WC, Mol, B, Whitaker, LHR, Jurkovic, D, Coomarasamy, A, Nunes, N, Holland, T, Clarke, F, Doust, AM, Daniels, J & for the GEM3 collaborative 2023, 'Combination of gefitinib and methotrexate to treat tubal ectopic pregnancy (GEM3): a multicentre, randomised, double-blind, placebo-controlled trial', The Lancet. https://doi.org/10.1016/S0140-6736(22)02478-3
GEM3 Collaborative Group 2023, 'Gefitinib and methotrexate to resolve tubal ectopic pregnancy: the GEM3 RCT', Efficacy and Mechanism Evaluation, vol. 10, no. 1. https://doi.org/0.3310/NNZF1037
Antoun, L, Middleton, L, Smith, P, Saridogan, E, Cooper, K, Brocklehurst, P, McKinnon, W, Bevan, S, Woolley, R, Jones, L, Fullard, J, Morgan, M, Roberts, T & Clark, TJ 2023, 'LAparoscopic Versus Abdominal hysterectomy (LAVA): protocol of a randomised controlled trial', BMJ open, vol. 13, no. 9, e070218. https://doi.org/10.1136/bmjopen-2022-070218
Martin, J, Middleton, L & Hemming, K 2023, 'Minimisation for the design of parallel cluster-randomised trials: An evaluation of balance in cluster-level covariates and numbers of clusters allocated to each arm', Clinical Trials, vol. 20, no. 2, pp. 111–120. https://doi.org/10.1177/17407745221149104
Paudyal, V, Lowrie, R, Mair, FS, Middleton, L, Cheed, V, Hislop, J, Williamson, A, Barnes, N, Jolly, K, Saunders, K, Allen, N, Jagpal, P, Provan, G, Ross, S, Hunter, C, Tearne, S, McPherson, A, Heath, H, Lombard, C, Araf, A, Dixon, E, Hatch, A, Moir, J & Akhtar, S 2023, 'Protocol for a pilot randomised controlled trial to evaluate integrated support from pharmacist independent prescriber and third sector worker for people experiencing homelessness: the PHOENIx community pharmacy study', Pilot and Feasibility Studies, vol. 9, no. 1, 29. https://doi.org/10.1186/s40814-023-01261-x
Gallos, I, Devall, A, Martin, J, Middleton, L, Beeson, L, Galadanci, H, Alwy al-Beity, F, Qureshi, Z, Hofmeyr, GJ, Moran, N, Fawcus, S, Sheikh, L, Gwako, G, Osoti, A, Aswat, A, Mammoliti, K, Sindhu, KN, Podesek, M, Horne, I, Timms, R, Yunas, I, Okore, J, Singata-Madliki, M, Arends, E, Wakili, AA, Mwampashi, A, Nausheen, S, Muhammad, S, Latthe, P, Evans, C, Akter, S, Forbes, G, Lissauer, D, Meher, S, Weeks, A, Shennan, A, Ammerdorffer, A, Williams, E, Roberts, T, Widmer, M, Oladapo, OT, Lorencatto, F, Bohren, MA, Miller, S, Althabe, F, Gülmezoglu, M, Smith, JM, Hemming, K & Coomarasamy, A 2023, 'Randomized Trial of Early Detection and Treatment of Postpartum Hemorrhage', New England Journal of Medicine, vol. 389, no. 1, pp. 11-21. https://doi.org/10.1056/NEJMoa2303966
Shelley, B, Goebel, A, Grant, S, Jackson, L, Jarrett, H, Jepson, M, Kerr, A, Marczin, N, Mehta, R, Melody, T, Middleton, L, Naidu, B, Szentgyorgyi, L, Tearne, S, Watkins, B, Wilson, M, Worrall, A, Yeung, J & Smith, FG 2023, 'Study protocol for a randomised controlled trial to investigate the effectiveness of thoracic epidural and paravertebral blockade in reducing chronic post-thoracotomy pain: 2 (TOPIC 2)', Trials, vol. 24, no. 1, 748. https://doi.org/10.1186/s13063-023-07463-1
Whitaker, LHR, Middleton, LJ, Daniels, JP, Williams, ARW, Priest, L, Odedra, S, Cheed, V, Stubbs, CE, Clark, TJ, Lumsden, M, Hapangama, DK, Bhattacharya, S, Smith, PP, Nicholls, EP, Roberts, N, Semple, SI, Saraswat, L, Walker, J, Chodankar, RR & Critchley, HOD 2023, 'Ulipristal acetate versus levonorgestrel-releasing intrauterine system for heavy menstrual bleeding (UCON): a randomised controlled phase III trial', EClinicalMedicine, vol. 60, pp. 101995. https://doi.org/10.1016/j.eclinm.2023.101995
Morton, V, Toozs-Hobson, P, Moakes, C, Moakes, C, Middleton, L, Daniels, J, Simpson, NAB, Shennan, A, Israfil-Bayli, F, Ewer, A, Gray, J, Slack, M, Norman, JE, Lees, C, Tryposkiadis, K, Hughes, M, Brocklehurst, P & Morris, RK 2022, 'Monofilament suture versus braided suture thread to improve pregnancy outcomes after vaginal cervical cerclage (C-STICH): a pragmatic randomised, controlled, phase 3, superiority trial', The Lancet, vol. 400, no. 10361, pp. 1426-1436. https://doi.org/10.1016/S0140-6736(22)01808-6
FEMME Trial Collaborative Group 2022, 'Uterine artery embolization or myomectomy for women with uterine fibroids: four-year follow-up of a randomised controlled trial', European Journal of Obstetrics & Gynecology and Reproductive Biology X, vol. 13, 100139. https://doi.org/10.1016/j.eurox.2021.100139
Israfil-Bayli, F, Morton, VH, Hewitt, CA, Ewer, AK, Gray, J, Norman, J, Lees, C, Simpson, NAB, Shennan, A, Tryposkiadis, K, Hughes, M, Daniels, J, Brocklehurst, P, Morris, K, Middleton, L & Toozs-Hobson, P 2021, 'C-STICH: Cerclage Suture Type for an Insufficient Cervix and its effect on Health outcomes—a multicentre randomised controlled trial', Trials, vol. 22, no. 1, 664. https://doi.org/10.1186/s13063-021-05629-3
Middleton, LJ 2021, 'Falling in the margin: Randomised controlled trials with a non-inferiority design', BJOG: An International Journal of Obstetrics and Gynaecology, vol. 128, no. 12, pp. 1916. https://doi.org/10.1111/1471-0528.16702
Hemming, K, Martin, J, Gallos, I, Coomarasamy, A, Middleton, L & E-MOTIVE study group 2021, 'Interim data monitoring in cluster randomised trials: practical issues and a case study', Clinical Trials, vol. 18, no. 5, pp. 552-561. https://doi.org/10.1177/17407745211024751
FEMME Trial Collaborative Group 2021, 'Uterine artery embolisation or myomectomy for women with uterine fibroids wishing to avoid hysterectomy: a cost–utility analysis of the FEMME trial', BJOG: An International Journal of Obstetrics & Gynaecology, vol. 128, no. 11, pp. 1793-1802. https://doi.org/10.1111/1471-0528.16781
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