Dr Matthew Armstrong is a Wellcome Trust Clinical Research Fellow (commenced Oct 2009). He qualified from Leeds Medical School in 2004 with honours, during which he obtained a 1st Class BSc in clinical sciences with research in small bowel surgery. His post-graduate training was undertaken in hospitals throughout the Yorkshire region, until he started his PhD at Birmingham University in 2009.
His keen interests lie in non-alcoholic fatty liver disease (NAFLD). His translation research involves a multicentre trial looking into the efficacy and mechanisms of a new group of diabetes drugs in NAFLD patients. He is a keen teacher.
Non-alcoholic fatty liver disease, non-invasive markers, liver function tests, Glucagon-like peptide 1 analogues.
NAFLD + GLP-1 analogues
Ongoing PhD studies involving Phase II Randomised Placebo-controlled Multi-centre Trial in NAFLD, including 2-step hyperinsulinaemic euglycaemic clamp and adipose microdialysis. In-vitro cell work looking at the direct effects of GLP-1 (receptor dependent vs non-dependent) on human hepatocytes and cell-lines.
Since 2009 he has presented his work at international liver and diabetes conferences.
Armstrong MJ, Houlihan DD, Bentham L, et al. Presence and Severity of Nonalcoholic Fatty Liver Disease in a Large, Prospective Primary Care Cohort. J Hepatol 2011 (accepted Mar 2011;in press)
Dowman JD, Armstrong MJ, Tomlinson JW, Newsome PN. Current Therapeutic Strategies in Nonalcoholic Fatty Liver Disease (NAFLD). Diabetes Obes Metab 2011 (accepted Mar 2011; in press)
Hegade VS, Armstrong MJ, Smithson JA. Hepatic Schistomiasis. QJM Nov 2010. [Epub ahead of print]
Armstrong MJ, Houlihan DD, Rowe IA. Pioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitis. N Engl J Med. 2010 Sep 16;363(12):1185; author reply 1186.
Armstrong MJ, Robins GG, Howdle PD. Recent advances in coeliac disease. Curr Opin Gastroenterol. 2009;25(2):100-9. Review.
Armstrong MJ, Booth C. Electronic health records in ambulatory care. N Engl J Med. 2008 Oct 23;359(17):1848; author reply 1849.
Robins GG, Sarwar MS, Armstrong MJ, et al. Evaluation of the need for endoscopy to identify low-risk patients presenting with an acute upper gastrointestinal bleed suitable for early discharge. Postgrad Med J. 2007 Dec;83(986):768-72.
Williams L, Armstrong MJ, Finan P, et al. The effect of faecal diversion on human ileum. Gut. 2007 Jun;56(6):796-801.