Dr Jennifer Marshall PhD


Research Associate

School of Immunity and Infection


Contact details

School of Immunity and Infection
College of Medical and Dental Sciences
Medical School Building
University of Birmingham
B15 2TT


Jennifer Marshall is a post doctoral research fellow working in Dr Kai-Micheal Toellner’s group in the School of Immunity and Infection.

She is currently investigating B cell immunosenescence and manipulation to provide better disease outcomes. Her previous post-doctoral work explored the role of different B cell subsets in antibody responses to bacterial antigens. This was preceded by a PhD studying B cell class switching and differentiation.


  • PhD in Immunology
  • BSc (Hons) in Natural Sciences (Genetics)


Other activities

Jennifer is a STEMNET volunteer and visits schools to talk on behalf of Understanding Animal Research.


The capsular polysaccharide Vi from Salmonella typhi is a B1b antigen.

Marshall JL, Flores-Langarica A, Kingsley RA, Hitchcock JR, Ross EA, López-Macías C, Lakey J, Martin LB, Toellner KM, MacLennan CA, MacLennan IC, Henderson IR, Dougan G, Cunningham AF.

Journal of Immunology. 2012 189, 5527-32

Systemic flagellin immunization stimulates mucosal CD103+ dendritic cells and drives Foxp3+ regulatory T cell and IgA responses in the mesenteric lymph node.

Flores-Langarica A, Marshall JL, Hitchcock J, Cook C, Jobanputra J, Bobat S, Ross EA, Coughlan RE, Henderson IR, Uematsu S, Akira S, Cunningham AF.

Journal of Immunology. 2012 189, 5745-54

Thymic function is maintained during Salmonella-induced atrophy and recovery.

Ross EA, Coughlan RE, Flores-Langarica A, Lax S, Nicholson J, Desanti GE, Marshall JL, Bobat S, Hitchcock J, White A, Jenkinson WE, Khan M, Henderson IR, Lavery GG, Buckley CD, Anderson G, Cunningham AF.

Journal of Immunology. 2012, 189, 4266-74.

Early B blasts acquire a capacity for Ig class switch recombination that is lost as they become plasmablasts.

Marshall JL, Zhang Y, Pallan L, Hsu MC, Khan M, Cunningham AF, MacLennan IC, Toellner KM.

European Journal of Immunology. 2011, 41, 3506-12.

CD31 is required on CD4+ T cells to promote T cell survival during Salmonella infection.

Ross EA, Coughlan RE, Flores-Langarica A, Bobat S, Marshall JL, Hussain K, Charlesworth J, Abhyankar N, Hitchcock J, Gil C, López-Macías C, Henderson IR, Khan M, Watson SP, MacLennan IC, Buckley CD, Cunningham AF.

Journal of Immunology. 2011, 187, 1553-65.

B cell priming for extrafollicular antibody responses requires Bcl-6 expression by T cells.

Lee SK, Rigby RJ, Zotos D, Tsai LM, Kawamoto S, Marshall JL, Ramiscal RR, Chan TD, Gatto D, Brink R, Yu D, Fagarasan S, Tarlinton DM, Cunningham AF, Vinuesa CG.

Journal of Experimental Medicine. 2011,208, 1377-88.

T-zone localized monocyte-derived dendritic cells promote Th1 priming to Salmonella.

Flores-Langarica A, Marshall JL, Bobat S, Mohr E, Hitchcock J, Ross EA, Coughlan RE, Khan M, Van Rooijen N, Henderson IR, Maclennan IC, Cunningham AF.

European Journal of Immunology. 2011, 41, 2654-65.

Soluble flagellin, FliC, induces an Ag-specific Th2 response, yet promotes T-bet-regulated Th1 clearance of Salmonella typhimurium infection.

Bobat S, Flores-Langarica A, Hitchcock J, Marshall JL, Kingsley RA, Goodall M, Gil-Cruz C, Serre K, Leyton DL, Letran SE, Gaspal F, Chester R, Chamberlain JL, Dougan G, López-Macías C, Henderson IR, Alexander J, MacLennan IC, Cunningham AF.

European Journal of Immunology. 2011, 41, 1606-18.

Absent bactericidal activity of mouse serum against invasive African nontyphoidal Salmonella results from impaired complement function but not a lack of antibody.

Siggins MK, Cunningham AF, Marshall JL, Chamberlain JL, Henderson IR, MacLennan CA.

Journal of Immunology. 2011,186, 2365-71.

Dysregulated humoral immunity to nontyphoidal Salmonella in HIV-infected African adults.

MacLennan CA, Gilchrist JJ, Gordon MA, Cunningham AF, Cobbold M, Goodall M, Kingsley RA, van Oosterhout JJ, Msefula CL, Mandala WL, Leyton DL, Marshall JL, Gondwe EN, Bobat S, López-Macías C, Doffinger R, Henderson IR, Zijlstra EE, Dougan G, Drayson MT, MacLennan IC, Molyneux ME.

Science. 2010, 328, 508-12.

The porin OmpD from nontyphoidal Salmonella is a key target for a protective B1b cell antibody response.

Gil-Cruz C, Bobat S, Marshall JL, Kingsley RA, Ross EA, Henderson IR, Leyton DL, Coughlan RE, Khan M, Jensen KT, Buckley CD, Dougan G, MacLennan IC, López-Macías C, Cunningham AF.

Proceedings of the National Academy of Sciences U S A. 2009, 106, 9803-8.

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