Dagmar Scheel-Toellner qualified as a pharmacist from the Christian-Albrechts University in Kiel, Germany in 1989. She went on to study for a PhD in the Department of Immunology and Cell Biology at the Research Centre Borstel with Professor Johannes Gerdes. In 1994 she was awarded the title Dr. rer. nat. (equivalent to PhD in Natural Sciences) by the Christian Albrechts University, Kiel for the thesis: “Investigation of the expression of CD26 in granulomatous tissue and normal peripheral blood.” with the grade “summa cum laude”. (Excellent)
In 1994 Dagmar moved to Birmingham to join the Department of Rheumatology as a post-doctoral research fellow with Mike Salmon and from 1996 also with Janet Lord.
She was awarded a Non-clinical Career Development Fellowship by the Arthritis Research Campaign (now renamed as Arthritis Research UK) in 2004. In the following years she established her research team and was promoted to Senior Research Fellow in 2007.
The Career Development Fellowship was followed by an Arthritis Research UK funded Career Progression Fellowship leading to a substantive post in the School of Immunity and Infection in 2010.
Hidalgo, E, Essex, S.F., Yeo, L. Curnow, S.J., Filer, A., Thomas, A.M, McGettrick, H. M. Cooper, M. Buckley, C.D., Raza, K., Salmon M. and Scheel-Toellner D. (2011), The response of T cells to IL-6 is differentially regulated by the microenvironment of the rheumatoid synovial fluid and tissue. Arthritis Rheum. 63 (11):3284-93.
Yeo, L, Toellner, K-M, Salmon, M., Filer, A., Buckley, C.D., Raza, K., and Scheel-Toellner, D. (2011), Cytokine mRNA profiling identifies B cells as a major source of RANKL in rheumatoid arthritis. Ann Rheum Dis. 70:2022-2028 Recommended in F1000, Highlighted in Nature Reviews in Rheumatology. (September 2011 | doi:10.1038/nrrheum.2011.114)
Lee, W.Y. Hampson, P. Coulthard, L., Ali, F., Salmon M, Lord J. M. and Scheel-Toellner D. (2010) Novel Anti-Leukemic Compound Ingenol 3-Angelate Inhibits T cell Apoptosis by Activating PKCTHETA J. Biol. Chem. Jul 30;285(31):23889-98
Church, L. D., Filer, A. D., Hidalgo, E., Howlett, K. A., Thomas, A.M.C., Rapecki, S., Scheel-Toellner, D., Buckley, C. D. and Raza, K. (2010) Rheumatoid synovial fluid IL-17-producing CD4 T cells have abundant TNF alpha co-expression, but little IL-22 and IL-23R expression Arthritis Research & Therapy;12(5):R184
Filer, A., Bik, M. Parsonage, G.M. Fitton, J., Trebilcock, E., Howlett, K. Cook, M. Raza, K Simmons, D. L. Thomas A. M. C., Salmon M. Scheel-Toellner, D. Lord, J. M. Rabinovich, G. A. and Buckley, C.D.(2009) Galectin 3 Induces a Distinctive Pattern of Cytokine and Chemokine Production in Rheumatoid Synovial Fibroblasts via Selective Signaling Pathways. Arthritis Rheum. Jun;60(6):1604-14.
Wong, S.H., Francis N., Chahal, H. Raza, K. , Salmon, M., Scheel-Toellner D and Lord J. M. (2009) Lactoferrin-induced neutrophil survival: Potential Role in Rheumatoid Arthritis. Rheumatology. Jan;48(1):39-44.
Scheel-Toellner, D., Raza, K., Assi, L.K., Pilling, D., Ross, E. J., Lee, W. Y., Curnow, S. J., Buckley, C. D., Akbar, A. N. Lord J. M. and Salmon M. (2008) Differential regulation of nuclear and mitochondrial Bcl-2 in T cell apoptosis. Apoptosis. 13(1):109-17.
Assi, L. K., Wong, S. H., Ludwig A., Raza, K., Gordon, C., Salmon, M. Lord J. M. and. Scheel-Toellner D. (2007) TNF-α activates release of BlyS by neutrophils infiltrating the rheumatoid joint. Arthritis Rheum. 56(6):1776-86.