The emerging role of CTLA-4 as a cell extrinsic regulator of T cell responses (2011) Lucy S.K. Walker and David M. Sansom. Nature Reviews Immunology (in press)
Qureshi, O.S., Y. Zheng, K. Nakamura, K. Attridge, C.N. Manzotti, E.M. Schmidt, J. Baker, L.E. Jeffery, S. Kaur, Z. Briggs, T.Z. Hou, C. Futter, G. Anderson, L.S.K. Walker, and D.M. Sansom. (2011) Trans-endocytosis of CD80 and CD86: A molecular basis for the cell extrinsic function of CTLA-4. Science 332(6029):600-603
Ryan GA, Wang CJ, Chamberlain JL, Attridge K, Schmidt EM, Kenefeck R, Clough LE, Dunussi-Joannopoulos K, Toellner KM, Walker L.S.K. (2010) B1 cells promote pancreas infiltration by autoreactive T cells. Journal of Immunology 185(5):2800-7
Walker L.S.K. (2009) Regulatory T cells overturned: the effectors fight back. Immunology 126(4):466-74.
Schmidt, E.M., C.J. Wang, G.A. Ryan, L.E. Clough, O.S. Qureshi, M. Goodall, A.K. Abbas, A.H. Sharpe, D.M. Sansom, and L.S.K. Walker. 2009. CTLA-4 controls regulatory T cell peripheral homeostasis and is required for suppression of pancreatic islet autoimmunity.
Journal of Immunology 182:274-282.
Qizhi Tang, Lucy S.K. Walker and Jeffrey A. Bluestone. (2008) Regulating Treg Cells at Sites of Inflammation. Immunity 29 (4):512
Clough, L.E., C.J. Wang, E.M. Schmidt, G. Booth, T.Z. Hou, R. G.A., and Lucy S.K. Walker. (2008) Release from Treg-mediated suppression during the onset of tissue-specific autoimmunity is associated with elevated IL-21. Journal of Immunology 180:5393-5401
Lucy S.K. Walker, Anna Chodos, Mark Eggena, Hans Dooms and Abul K. Abbas. (2003) Antigen-specific proliferation of CD4+CD25+ regulatory T cells in vivo. Journal of Experimental Medicine 198(2):249-258.