David graduated from Monash University, Melbourne in 1980 and commenced specialist training in Internal Medicine and Gastroenterology in Melbourne.
In 1986 he came to the UK and worked as research fellow at the University of Newcastle-upon-Tyne from 1986-89. From 1987-89 he held the British Digestive Foundation Amelia Waring Research Fellowship.
In 1989 he moved to the Birmingham Queen Elizabeth Hospital Liver Unit, and has worked there since that time. In 1996 he was appointed Senior Lecturer then Reader in Hepatology (B'ham University) and Honorary Consultant Hepatologist to the Liver and Hepatobiliary Unit. He was Clinical Service Lead for Hepatology at the Queen ElizabethHospital from 2000 to 2010.
In the field of hepatitis infection, he has focused on antiviral treatment, drug resistance, epidemiology and natural history of infection. In the field of liver transplantation, his principal interests have included the treatment and prevention of recurrent viral hepatitis and opportunistic infections.
He is a fellow of the Royal College of Physicians of England and AustralasianCollege of Physicians. He acts as adviser to the Department of Health on issues related to viral hepatitis and liver transplantation, and is a founder and trustee of the charity, Hepatitis B Foundation UK.
He has published more than 100 original and invited articles in peer-reviewed journals. He was associate editor of Gut (2007-9) and is now a member of the editorial boards of Gut, the Journal of Hepatology, Liver Transplantation, and Alimentary Pharmacology and Therapeutics.