Dr Jianmin Zuo MBBS, PhD

 Dr Jianmin Zuo

Institute of Immunology and Immunotherapy
Associate Professor in Immunology

Contact details

Address
Institute of Immunology and Immunotherapy
CRC building
College of Medical and Dental Sciences
University of Birmingham
Birmingham
B15 2TT

Jianmin Zuo is an Associate Professor in Immunology from the Institute of Immunology and Immunotherapy.

His research focusses are viral immunology and cancer immunology. He is interested in the development of cellular therapeutic agents to target viral-related diseases and cancers.

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Qualifications

  • PhD Immunology, 2004

Biography

After PhD training in Beijing China, Jianmin Zuo obtained a research training fellowship from IARC (WHO) to join the EBV immunology group in Birmingham at 2004.

He has been working on viral immunology for more than 20 years in EBV, CMV and recently COVID-19. He also has been studying the immune modulation of Natural Killer (NK) cells in Cancers, including Leukemia and Solid Cancers. 

The inspiration is to explore the potential of NK cells based immunotherapy to treat cancers.

Teaching

  • Immunity and Infection, BMedSci, year 2
  • MSc Immunology and Immunotherapy
  • MRes Cancer Sciences

Postgraduate supervision

Viral Immunology
Cancer Immunology

Jianmin Zuo is happy to discuss opportunities to undertake research study in his laboratory, either in the areas described in his research biography or in other settings.

If you are interesting in studying any of these subject areas please contact Dr Jianmin Zuo directly, or for any general doctoral research enquiries, please email mds-gradschool@contacts.bham.ac.uk.

For a full list of available Doctoral Research opportunities, please visit our Doctoral Research programme listings.

Research

Jianmin Zuo's work focus on Viral and Cancer Immunology,

Immunology of EBV/CMV infection

We study the T/NK cellular immune responses against EBV/CMV infection over the life course.

Immune modulation of Natural Killer (NK) cells in Cancers

We study the immune modulation of NK cells by Cancer and explore the approaches of NK cells based Immunotherapy. 

Publications

Recent publications

Article

Verma, K, Croft, W, Greenwood, D, Stephens, C, Malladi, R, Nunnick, J, Zuo, J, Kinsella, FAM & Moss, P 2024, 'Early inflammatory markers as prognostic indicators following allogeneic stem cell transplantation', Frontiers in immunology, vol. 14, 1332777. https://doi.org/10.3389/fimmu.2023.1332777

Ladhani, SN, Dowell, AC, Jones, S, Hicks, B, Rowe, C, Begum, J, Wailblinger, D, Wright, J, Owens, S, Pickering, A, Shilltoe, B, McMaster, P, Whittaker, E, Zuo, J, Powell, A, Amirthalingam, G, Mandal, S, Lopez-Bernal, J, Ramsay, ME, Kissane, N, Bell, M, Watson, H, Ho, D, Hallis, B, Otter, A, Moss, P & Cohen, J 2023, 'Early evaluation of the safety, reactogenicity, and immune response after a single dose of modified vaccinia Ankara-Bavaria Nordic vaccine against mpox in children: a national outbreak response', The Lancet Infectious Diseases, vol. 23, no. 9, pp. 1042-1050. https://doi.org/10.1016/S1473-3099(23)00270-0

Verma, K, Croft, W, Pearce, H, Zuo, J, Stephens, C, Nunnick, J, Kinsella, F, Malladi, R & Moss, P 2023, 'Early expression of CD94 and loss of CD96 on CD8+ T cells after allogeneic SCT is predictive of subsequent relapse and survival', Haematologica, vol. 108, no. 2, pp. 433-443. https://doi.org/10.3324/haematol.2021.280497

Dowell, AC, Lancaster, T, Bruton, R, Ireland, G, Bentley, C, Sylla, P, Zuo, J, Scott, S, Jadir, A, Begum, J, Roberts, T, Stephens, C, Ditta, S, Shepherdson, R, Powell, AA, Brent, AJ, Brent, B, Baawuah, F, Okike, I, Beckmann, J, Ahmad, S, Aiano, F, Garstang, J, Ramsay, ME, Azad, R, Waiblinger, D, Willett, B, Wright, J, Ladhani, SN & Moss, P 2023, 'Immunological imprinting of humoral immunity to SARS-CoV-2 in children', Nature Communications, vol. 14, no. 1, 3845. https://doi.org/10.1038/s41467-023-39575-2

Dowell, AC, Tut, G, Begum, J, Bruton, R, Bentley, C, Butler, M, Uwenedi, G, Zuo, J, Powell, AA, Brent, AJ, Brent, B, Baawuah, F, Okike, I, Beckmann, J, Ahmad, S, Aiano, F, Garstang, J, Ramsay, ME, Moss, P & Ladhani, SN 2023, 'Nasal mucosal IgA levels against SARS-CoV-2 and seasonal coronaviruses are low in children but boosted by reinfection', Journal of Infection, vol. 87, no. 5, pp. 403-412. https://doi.org/10.1016/j.jinf.2023.08.013

Croft, W, Pearce, H, Margielewska-Davies, S, Lim, L, Nicol, SM, Zayou, F, Blakeway, D, Marcon, F, Powell-Brett, S, Mahon, B, Merard, R, Zuo, J, Middleton, G, Roberts, K, Brown, RM, Moss, P & Ng, T 2023, 'Spatial determination and prognostic impact of the fibroblast transcriptome in pancreatic ductal adenocarcinoma', eLife, vol. 12, 86125. https://doi.org/10.7554/elife.86125

Hassan, N, Eldershaw, S, Stephens, C, Kinsella, F, Craddock, C, Malladi, R, Zuo, J & Moss, P 2022, 'CMV reactivation initiates long-term expansion and differentiation of the NK cell repertoire', Frontiers in immunology, vol. 13, 935949. https://doi.org/10.3389/fimmu.2022.935949

Dowell, AC, Butler, MS, Jinks, E, Tut, G, Lancaster, T, Sylla, P, Begum, J, Bruton, R, Pearce, H, Verma, K, Logan, N, Tyson, G, Spalkova, E, Margielewska-Davies, S, Taylor, GS, Syrimi, E, Baawuah, F, Beckmann, J, Okike, IO, Ahmad, S, Garstang, J, Brent, AJ, Brent, B, Ireland, G, Aiano, F, Amin-Chowdhury, Z, Jones, S, Borrow, R, Linley, E, Wright, J, Azad, R, Waiblinger, D, Davis, C, Thomson, EC, Palmarini, M, Willett, BJ, Barclay, WS, Poh, J, Amirthalingam, G, Brown, KE, Ramsay, ME, Zuo, J, Moss, P & Ladhani, S 2022, 'Children develop robust and sustained cross-reactive spike-specific immune responses to SARS-CoV-2 infection', Nature Immunology, vol. 23, no. 1, pp. 40-49. https://doi.org/10.1038/s41590-021-01089-8

Parry, H, Moss, P, Stephens, C, Bentley, C, Brown, K, Amirthalingam, G, Hallis, B, Otter, A, Zuo, J & Moss, P 2022, 'Extended interval BNT162b2 vaccination enhances peak antibody generation', NPJ vaccines, vol. 7, no. 1, 14. https://doi.org/10.1038/s41541-022-00432-w

Parry, H, McIlroy, G, Moss, P, Damery, S, Tyson, G, Logan, N, Davis, C, Willett, B, Zuo, J, Ali, M, Kaur, M, Stephens, C, Brant, D, Otter, A, McSkeane, T, Rolfe, H, Faustini, S, Richter, A, Lee, S, Wandroo, F, Shafeek, S, Pratt, G, Paneesha, S & Moss, P 2022, 'Impaired neutralisation of SARS-CoV-2 delta variant in vaccinated patients with B cell chronic lymphocytic leukaemia', Journal of Hematology and Oncology, vol. 15, no. 1, 3. https://doi.org/10.1186/s13045-021-01219-7

Tut, G, Lancaster, T, Butler, MS, Sylla, P, Spalkova, E, Bone, D, Kaur, N, Bentley, C, Amin, U, Jadir, AT, Hulme, S, Ayodel, M, Dowell, AC, Pearce, H, Zuo, J, Margielewska-Davies, S, Verma, K, Nicol, S, Begum, J, Jinks, E, Tut, E, Moss, P, Krutikov, M, Shrotri, M, Giddings, R, Azmi, B, Fuller, C, Irwin-Singer, A, Hayward, A, Copas, A, Shallcross, L & Moss, P 2022, 'Robust SARS-CoV-2-specific and heterologous immune responses in vaccine-naïve residents of long-term care facilities who survive natural infection', Nature Aging, vol. 2, no. 6, pp. 536-547. https://doi.org/10.1038/s43587-022-00224-w

Letter

Roberts, T, Uwenedi, G, Bruton, R, McIlroy, G, Damery, S, Sylla, P, Logan, N, Scott, S, Lau, M, Elzaidi, A, Plass, S, Mallick, S, Spencer, K, Stephens, C, Bentley, C, Pratt, G, Zuo, J, Paneesha, S, Willett, B, Moss, P & Parry, H 2024, 'Enhancement of Omicron-specific immune responses following bivalent COVID-19 booster vaccination in patients with chronic lymphocytic leukaemia', Blood Cancer Journal, vol. 14, no. 1, 22. https://doi.org/10.1038/s41408-023-00940-5

Parry, H, Moss, P, Uwenedi, G, Roberts, T, Sylla, P, Cook, J, Elzaidi, A, Lau, M, Drury, T, Bray, A, Mallick, S, Spencer, K, Bentley, C, Mcilroy, G, Scott, S, Logan, N, Zuo, J, Willett, B & Moss, P 2023, 'Robust generation of neutralising antibodies against Omicron variants following bivalent mRNA booster vaccine in elderly people aged >80 years', Journal of Infection. https://doi.org/10.1016/j.jinf.2023.08.014

Parry, H, Bruton, R, Roberts, T, Mcilroy, G, Damery, S, Sylla, P, Dowell, AC, Tut, G, Lancaster, T, Bone, D, Willett, B, Logan, N, Scott, S, Hulme, S, Jadir, A, Amin, U, Nicol, S, Stephens, C, Faustini, S, Al-taei, S, Richter, A, Blakeway, D, Verma, K, Margielewska-davies, S, Pearce, H, Pratt, G, Zuo, J, Paneesha, S & Moss, P 2022, 'COVID-19 vaccines elicit robust cellular immunity and clinical protection in chronic lymphocytic leukemia', Cancer Cell, vol. 40, no. 6, pp. 584-586. https://doi.org/10.1016/j.ccell.2022.05.001

Preprint

Croft, W, Pearce, H, Margielewska-Davies, S, Lim, L, Nicol, SM, Zayou, F, Blakeway, D, Marcon, F, Powell-Brett, S, Mahon, B, Merard, R, Zuo, J, Middleton, G, Roberts, K, Brown, RM & Moss, P 2023 'Spatial determination and prognostic impact of the fibroblast transcriptome in pancreatic ductal adenocarcinoma' bioRxiv. https://doi.org/10.1101/2023.01.20.524883

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