Coltman, N. J., Rochford, G., Hodges, N. J., Ali-Boucetta, H., Barlow, J. P. Exploring Mitochondrial Energy Metabolism of Single 3D Microtissue Spheroids using Extracellular Flux Analysis. J. Vis. Exp. (180), e63346, doi:10.3791/63346 (2022)
Daniel G. Sadler, Jonathan Barlow, Richard Draijer, Helen Jones, Dick H. J. Thijssen, Claire E. Stewart, "(–)-Epicatechin Alters Reactive Oxygen and Nitrogen Species Production Independent of Mitochondrial Respiration in Human Vascular Endothelial Cells", Oxidative Medicine and Cellular Longevity, vol. 2022, Article ID 4413191, 13pages, 2022. https://doi.org/10.1155/2022/4413191
Prolyl-4-hydroxylase 3 maintains β cell glucose metabolism during fatty acid excess in mice. (2021). Prolyl-4-hydroxylase 3 maintains β cell glucose metabolism during fatty acid excess in mice. 6 (16). http://doi.org/10.1172/jci.insight.140288
Jonathan P. Barlow, Kristian Karstoft, Andreas Vigelsø, Martin Gram, Jørn W. Helge, Flemming Dela, Kirk Pappan, Donna O’Neil, Warwick Dunn, Thomas P.J. Solomon,Beta-aminoisobutyric acid is released by contracting human skeletal muscle and lowers insulin release from INS-1 832/3 cells by mediating mitochondrial energy metabolism,Metabolism Open,Volume 7, 2020,100053,ISSN 2589-9368, https://doi.org/10.1016/j.metop.2020.100053
Seabright, A. P., Fine, N. H. F., Barlow, J. P., Lord, S. O., Musa, I., Gray, A., et al. (2020). AMPK activation induces mitophagy and promotes mitochondrial fission while activating TBK1 in a PINK1-Parkin independent manner. FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology, 34(5), 6284–6301. http://doi.org/10.1096/fj.201903051R
Barlow, J. and Solomon, T. (2018). Conditioned media from contracting skeletal muscle potentiates insulin secretion and enhances mitochondrial energy metabolism of pancreatic beta-cells. Metabolism. Impact factor: 5.963. PMID: 30445139
Barlow, J., Carter, S., and Solomon, T. (2018). Skeletal muscle to pancreatic beta-cell crosstalk: Probing the effect of IL-6 on insulin secretion by INS-1 832/3 insulinoma cells under diabetic-like conditions. International journal of Molecular Sciences. Impact Factor: 3.226. PMID: 29966345
Barlow, J., Solomon, T., and Affourtit, C. (2018). Pro-inflammatory cytokines attenuate glucose-stimulated insulin secretion from INS-1E insulinoma cells by restricting mitochondrial pyruvate oxidation capacity – novel mechanistic insight from real-time analysis of oxidative phosphorylation. PLOS one. Impact factor: 2.806. PMID: 29953508
Affourtit, C., Alberts, B., Barlow, J., Carré, J. and Wynne, A. (2018). Control of pancreatic β-cell bioenergetics. Biochemical Society Transactions. Impact factor: 2.765. PMID: 29666215
Barlow, J. and Solomon, T. (2017). Do skeletal muscle-secreted factors influence the function of pancreatic beta cells? AJP Endocrinology and Metabolism. Impact factor: 4.142. PMID: 29208613
Barlow J, Jensen VH, Jastroch M, and Affourtit C. (2016) Palmitate-induced impairment of glucose-stimulated insulin secretion precedes mitochondrial dysfunction in mouse pancreatic islets. Biochemical Journal. 4, 487–96. Impact factor: 3.797. PMID: 26621874
Barlow, J., Hirschburg, V. and Affourtit, C. (2014) Uncoupling protein-2 attenuates palmitoleate protection against the cytotoxic production of mitochondrial reactive oxygen species in INS-1E insulinoma cells. Redox Biology. 4, 14-22. Impact Factor: 6.337. PMID: 25482405
Barlow, J. and Affourtit, C. (2013) Novel insights in pancreatic beta cell glucolipotoxicity from real-time functional analysis of mitochondrial energy metabolism in INS-1E insulinoma cells. Biochemical Journal. 456, 417-426. Impact Factor: 3.797. PMID: 24099598
Barlow, J., Hirschberg, V., Brand, M. D. and Affourtit, C. (2013) Measuring Mitochondrial Uncoupling Protein-2 Level and Activity in Insulinoma Cells. Methods of Enzymology. 528, 257–267. Impact Factor: 1.972. PMID: 23849870
Barlow, J., Hirschberg, V. and Affourtit, C. (2013). On the role of mitochondria in pancreatic beta cells. In: Research on Diabetes 1 (ISBN: 978-1-922227-21-8), edited by iConcept Press, printed in Hong Kong.