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Understanding brain function and brain diseases are major intellectual and practical challenges facing mankind. Neuroscience in the School of Clinical and Experimental Medicine has research strengths in:

• Neurodegenerative diseases 
• Neurodegeneration and repair 
• Neuronal function and dysfunction 
• Psychiatry

It spans basic and clinical research, at levels of analysis from the molecular to the whole organism. It has strong collaborative links with the Birmingham Clinical Trials Unit and with the wider neuroscience community in the Colleges of Life and Environmental Sciences and Engineering.

Research is performed in specialised laboratories for:

• Molecular neurology 
• Molecular neuroscience 
• Cellular neuroscience 
• Cellular and systems electrophysiology
• Imaging and neuropharmacology

Clinical studies are centred on the Clinical Neuroscience Unit in the Queen Elizabeth Hospital, the Academic Psychiatry Unit in the Queen Elizabeth Psychiatric Hospital (QEPH), and through field teams based at the QEPH.

Related links
School of Clinical and Experimental Medicine website: www.clinexpmed.bham.ac.uk  

• Investigation of the molecular mechanisms underlying chronic neurodegenerative diseases such as Parkinson's disease and motor neurone disease; candidate gene screening approaches to various neurological disorders.
  Contact: Professor Karen Morrison
  Email: k.morrison@bham.ac.uk
• Clinical trials of therapies in Parkinson’s and motor neurone disease.
  Contact: Professor Karen Morrison
  Email: k.morrison@bham.ac.uk
  Professor Carl Clarke
  Email: c.e.clarke@bham.ac.uk
• Cellular and genetic mechanisms underlying Alzheimer’s disease; developmental causes of epilepsy.
  Contact: Dr Zsuzsanna Nagy
  Email: z.nagy@bham.ac.uk
• Clinical trials of therapies (pharmacological and surgical) in Parkinson's disease.
  Contact: Dr Carl Clarke
  Email: c.e.clarke@bham.ac.uk
• Acute trauma, and neurodegeneration; understanding mechanisms of natural ageing; evaluation of novel gene- and cell-based therapeutic strategies for central nervous system (CNS) repair.
  Contact: Professor Ann Logan
  Email: a.logan@bham.ac.uk
  Dr Ana-Maria Gonzalez
  Email: a.m.gonzalez.1@bham.ac.uk
• Basic mechanisms of temporal lobe epilepsy; fast physiological oscillations associated with cognition; physiology and pathophysiology of prion protein; effects of electric fields on brain function; pathophysiology of X-linked mental retardation.
  Contact: Professor John Jefferys
  Email: j.g.r.jefferys@bham.ac.uk
  Dr Andrew Powell
  Email: a.d.powell@bham.ac.uk
• Structure and operation of cortical networks investigated by cellular electrophysiology, immunohistochemistry, and light and electron microscopy; physiological oscillations associated with cognition; basic mechanisms of epilepsy; quantification of synaptic networks.
  Contact: Professor Attila Sik
  Email: a.sik@bham.ac.uk
• Role of intracellular calcium pools in integration of neuronal functions; mitochondrial function in normal ageing and aged neurons.
  Contact: Dr Emil Toescu
  Email: e.c.toescu@bham.ac.uk
• Panic, neurosteroids and the female brain; cerebral circulation.
  Contact: Dr Thelma Lovick
  Email: t.a.lovick@bham.ac.uk
• Basic mechanisms of temporal lobe epilepsy; fast physiological oscillations associated with cognition; neurophysiology of normal ageing.
  Contact: Dr Martin Vreugdenhil
  Email: m.vreugdenhil@bham.ac.uk