Molecular mechanisms in immune cell differentiation and function (20 credits)
This module will provide an in depth knowledge of the development of primary and secondary lymphoid structures, and how T and B cells differentiate within these environments. Cutting-edge knowledge will also be developed in the activation and functional diversity of T and B cell responses, including the formation of germinal centres, T helper cell differentiation and regulatory T cell function. The cellular requirements, molecules and their associated signalling pathways, required for each of these processes will be covered. The module will contain a combination of face-to-face lectures integrated with a series of small group teaching sessions to provide further tuition and clarification of understanding.
Module attendance required: Three weeks of lectures and small group tutorials.
Module dates: TBC
Assessment:
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Examination (75%):
2 written essays. (2h exam)
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Coursework (25%):
Course work will consist of a written 1500 word summary document and oral presentation of a given research topic, bringing together information from a number of cutting-edge research publications. Length of presentation limited to 25 minutes with 5 minutes for questions.
Academics involved in the delivery of this module:
Dr Jorge Caamano (Institute for Biomedical Research) and Dr John Curnow (Centre for Translational Inflammation Research),
and a number of other researchers from across the College of Medical and Dental Sciences, including Prof. Peter Cockerill, Prof. Adam Cunningham, Dr Will Jenkinson, Dr Kai Toellner, and Dr David Withers.