This level 3 module utilises the principles and concepts developed through pre-requisite modules (Synthesis and Mechanism I and II). The module covers aspects of synthetic organic chemistry (organo-element chemistry; medicinally active compounds; and synthetic strategy and planning), physical organic chemistry (diagnosis of mechanism; isotope effects), applied FMO and stereoelectronic effects (pericyclic reactions; anomeric effect; Baldwin's rules), and reactive intermediates.